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Persistent Genital Human Papillomavirus Infection as a Risk Factor for Persistent Cervical Dysplasia

Persistent Genital Human Papillomavirus Infection as a Risk Factor for Persistent Cervical Dysplasia Downloaded from https://academic.oup.com/jnci/article-abstract/87/18/1365/927916 by guest on 14 October 2019 Persistent Genital Human Papillomavirus Infection as a Risk Factor for Persistent Cervical Dysplasia Gloria Y. F. Ho, Robert D. Burk, Sara Klein, Anna S. Kadish, C. J. Chang, Prabhudas Palan, Jayasri Basu, Ruth Tachezy, Renee Lewis, Seymour Romney* the prognosis of cervical dysplasia as measured by persis- tence of the lesion. Testing for HPV infection may be valu- Background: Cervical dysplasia, also referred to as able in the clinical management of women with cervical squamous intraepithelial lesion (SIL) in cytology or cervical dysplasia. [J Natl Cancer Inst 1995;87:1365-71] intraepithelial neoplasia in histopathology, is thought to have the potential to advance in progressive stages to cervi- cal cancer. However, not all cases of SIL progress, and most Cervical dysplasia, also referred to as squamous intraepithelial of the mild lesions spontaneously regress. Factors that lesion (SIL) in cytology or cervical intraepithelial neoplasia govern regression, persistence, and progression of SIL are (CIN) in histopathology, can be classified into grades I, II, and poorly understood. Purpose: Our analysis sought to identify III. This grading system assumes that the severity of CIN repre- factors that determined persistence or regression of SIL. sents a morphologic and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JNCI: Journal of the National Cancer Institute Oxford University Press

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Publisher
Oxford University Press
Copyright
© Oxford University Press
ISSN
0027-8874
eISSN
1460-2105
DOI
10.1093/jnci/87.18.1365
Publisher site
See Article on Publisher Site

Abstract

Downloaded from https://academic.oup.com/jnci/article-abstract/87/18/1365/927916 by guest on 14 October 2019 Persistent Genital Human Papillomavirus Infection as a Risk Factor for Persistent Cervical Dysplasia Gloria Y. F. Ho, Robert D. Burk, Sara Klein, Anna S. Kadish, C. J. Chang, Prabhudas Palan, Jayasri Basu, Ruth Tachezy, Renee Lewis, Seymour Romney* the prognosis of cervical dysplasia as measured by persis- tence of the lesion. Testing for HPV infection may be valu- Background: Cervical dysplasia, also referred to as able in the clinical management of women with cervical squamous intraepithelial lesion (SIL) in cytology or cervical dysplasia. [J Natl Cancer Inst 1995;87:1365-71] intraepithelial neoplasia in histopathology, is thought to have the potential to advance in progressive stages to cervi- cal cancer. However, not all cases of SIL progress, and most Cervical dysplasia, also referred to as squamous intraepithelial of the mild lesions spontaneously regress. Factors that lesion (SIL) in cytology or cervical intraepithelial neoplasia govern regression, persistence, and progression of SIL are (CIN) in histopathology, can be classified into grades I, II, and poorly understood. Purpose: Our analysis sought to identify III. This grading system assumes that the severity of CIN repre- factors that determined persistence or regression of SIL. sents a morphologic and

Journal

JNCI: Journal of the National Cancer InstituteOxford University Press

Published: Sep 20, 1995

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