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The activation of P2Y2 receptors increases MCF-7 breast cancer cells migration through the MEK-ERK1/2 signalling pathway

The activation of P2Y2 receptors increases MCF-7 breast cancer cells migration through the... SummaryExtracellular ATP importantly increases the migration of human MCF-7 breast cancer cells. This pro-migratory effect, critical for the development of metastases, is mediated by the activation of the UTP-sensitive P2Y2 receptor and the downstream activation of a MEK-ERK1/2-dependent signalling pathway. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Carcinogenesis Oxford University Press

The activation of P2Y2 receptors increases MCF-7 breast cancer cells migration through the MEK-ERK1/2 signalling pathway

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References (59)

Publisher
Oxford University Press
Copyright
© The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com
Subject
Original Manuscript
ISSN
0143-3334
eISSN
1460-2180
DOI
10.1093/carcin/bgt493
pmid
24390819
Publisher site
See Article on Publisher Site

Abstract

SummaryExtracellular ATP importantly increases the migration of human MCF-7 breast cancer cells. This pro-migratory effect, critical for the development of metastases, is mediated by the activation of the UTP-sensitive P2Y2 receptor and the downstream activation of a MEK-ERK1/2-dependent signalling pathway.

Journal

CarcinogenesisOxford University Press

Published: Jun 3, 2014

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