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Augmentation Strategies in Electroconvulsive Therapy: A Synthesis.

Augmentation Strategies in Electroconvulsive Therapy: A Synthesis. Over the past four decades, a variety of pharmacological augmentation strategies have been used in electroconvulsive therapy (ECT). Their goal has been to enhance therapeutic effects and seizure manifestations, or to minimize cognitive effects. Although they are not intended to affect outcome or other clinical parameters, medications taken during ECT may also impact on safety and efficacy. There is a large literature in epileptology on how pharmacologic agents affect seizure physiology. We review the clinical literature on augmentation strategies in ECT, with a synopsis of relevant preclinical studies, and seek to relate the pharmacological effects on seizure parameters to critical clinical variables in ECT. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Convulsive therapy Pubmed

Augmentation Strategies in Electroconvulsive Therapy: A Synthesis.

Convulsive therapy , Volume 9 (4): 21 – Apr 9, 2002

Augmentation Strategies in Electroconvulsive Therapy: A Synthesis.


Abstract

Over the past four decades, a variety of pharmacological augmentation strategies have been used in electroconvulsive therapy (ECT). Their goal has been to enhance therapeutic effects and seizure manifestations, or to minimize cognitive effects. Although they are not intended to affect outcome or other clinical parameters, medications taken during ECT may also impact on safety and efficacy. There is a large literature in epileptology on how pharmacologic agents affect seizure physiology. We review the clinical literature on augmentation strategies in ECT, with a synopsis of relevant preclinical studies, and seek to relate the pharmacological effects on seizure parameters to critical clinical variables in ECT.

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ISSN
0749-8055
pmid
11941229

Abstract

Over the past four decades, a variety of pharmacological augmentation strategies have been used in electroconvulsive therapy (ECT). Their goal has been to enhance therapeutic effects and seizure manifestations, or to minimize cognitive effects. Although they are not intended to affect outcome or other clinical parameters, medications taken during ECT may also impact on safety and efficacy. There is a large literature in epileptology on how pharmacologic agents affect seizure physiology. We review the clinical literature on augmentation strategies in ECT, with a synopsis of relevant preclinical studies, and seek to relate the pharmacological effects on seizure parameters to critical clinical variables in ECT.

Journal

Convulsive therapyPubmed

Published: Apr 9, 2002

There are no references for this article.