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Biofortified tomatoes provide a new route to vitamin D sufficiency.

Biofortified tomatoes provide a new route to vitamin D sufficiency. Poor vitamin D status is a global health problem; insufficiency underpins higher risk of cancer, neurocognitive decline and all-cause mortality. Most foods contain little vitamin D and plants are very poor sources. We have engineered the accumulation of provitamin D3 in tomato by genome editing, modifying a duplicated section of phytosterol biosynthesis in Solanaceous plants, to provide a biofortified food with the added possibility of supplement production from waste material. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Plants Pubmed

Biofortified tomatoes provide a new route to vitamin D sufficiency.

Biofortified tomatoes provide a new route to vitamin D sufficiency.


Abstract

Poor vitamin D status is a global health problem; insufficiency underpins higher risk of cancer, neurocognitive decline and all-cause mortality. Most foods contain little vitamin D and plants are very poor sources. We have engineered the accumulation of provitamin D3 in tomato by genome editing, modifying a duplicated section of phytosterol biosynthesis in Solanaceous plants, to provide a biofortified food with the added possibility of supplement production from waste material.

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References (42)

Copyright
© 2022. The Author(s).
eISSN
2055-0278
DOI
10.1038/s41477-022-01154-6
pmid
35606499

Abstract

Poor vitamin D status is a global health problem; insufficiency underpins higher risk of cancer, neurocognitive decline and all-cause mortality. Most foods contain little vitamin D and plants are very poor sources. We have engineered the accumulation of provitamin D3 in tomato by genome editing, modifying a duplicated section of phytosterol biosynthesis in Solanaceous plants, to provide a biofortified food with the added possibility of supplement production from waste material.

Journal

Nature PlantsPubmed

Published: Jun 23, 2022

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