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Circulating tumour-derived predictive biomarkers in oncology.

Circulating tumour-derived predictive biomarkers in oncology. Molecular characterization of tumour material will become increasingly important in selecting patients for clinical trials and offering appropriate treatment for patients in clinical practice. Recent advances in the field have indicated that the molecular characteristics of a tumour can be determined from circulating tumour cells and circulating tumour DNA; thus, a simple blood sample could provide these data in a simple, convenient and efficient manner. This article discusses progress towards guiding treatment decisions through measuring tumour-derived factors in the circulation. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Drug discovery today Pubmed

Circulating tumour-derived predictive biomarkers in oncology.

Circulating tumour-derived predictive biomarkers in oncology.


Abstract

Molecular characterization of tumour material will become increasingly important in selecting patients for clinical trials and offering appropriate treatment for patients in clinical practice. Recent advances in the field have indicated that the molecular characteristics of a tumour can be determined from circulating tumour cells and circulating tumour DNA; thus, a simple blood sample could provide these data in a simple, convenient and efficient manner. This article discusses progress towards guiding treatment decisions through measuring tumour-derived factors in the circulation.

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ISSN
1359-6446
DOI
10.1016/j.drudis.2009.12.006
pmid
20045486

Abstract

Molecular characterization of tumour material will become increasingly important in selecting patients for clinical trials and offering appropriate treatment for patients in clinical practice. Recent advances in the field have indicated that the molecular characteristics of a tumour can be determined from circulating tumour cells and circulating tumour DNA; thus, a simple blood sample could provide these data in a simple, convenient and efficient manner. This article discusses progress towards guiding treatment decisions through measuring tumour-derived factors in the circulation.

Journal

Drug discovery todayPubmed

Published: Apr 27, 2010

There are no references for this article.