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Clinical and Molecular Features of Late Onset Huntington Disease in a Peruvian Cohort.

Clinical and Molecular Features of Late Onset Huntington Disease in a Peruvian Cohort. Late onset cases of Huntington disease (HD), with onset ≥60 years, account for up to 20% of HD cases worldwide. Clinical features include mild motor dysfunction with slow progression and cognitive impairment, frequent absence of family history and low number of CAG repeats. The clinical and molecular features of late onset HD is still understudied in Latin America. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Huntington's disease Pubmed

Clinical and Molecular Features of Late Onset Huntington Disease in a Peruvian Cohort.

Clinical and Molecular Features of Late Onset Huntington Disease in a Peruvian Cohort.


Abstract

Late onset cases of Huntington disease (HD), with onset ≥60 years, account for up to 20% of HD cases worldwide. Clinical features include mild motor dysfunction with slow progression and cognitive impairment, frequent absence of family history and low number of CAG repeats. The clinical and molecular features of late onset HD is still understudied in Latin America.

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ISSN
1879-6397
pmid
26333261

Abstract

Late onset cases of Huntington disease (HD), with onset ≥60 years, account for up to 20% of HD cases worldwide. Clinical features include mild motor dysfunction with slow progression and cognitive impairment, frequent absence of family history and low number of CAG repeats. The clinical and molecular features of late onset HD is still understudied in Latin America.

Journal

Journal of Huntington's diseasePubmed

Published: Oct 30, 2015

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