Get 20M+ Full-Text Papers For Less Than $1.50/day. Subscribe now for You or Your Team.

Learn More →

Higher risk of lung cancer in chronic obstructive pulmonary disease. A prospective, matched, controlled study.

Higher risk of lung cancer in chronic obstructive pulmonary disease. A prospective, matched,... To assess the risk of lung cancer in patients with chronic obstructive pulmonary disease, we matched, on the basis of age, sex, occupation, and smoking history, 113 persons ("cases") who had a forced expiratory volume in 1 second (FEV1) of 70% or less of predicted normal with 113 control persons who had an FEV1 of 85% or more. All persons were observed from 1973-74 through 1984 for a diagnosis of lung cancer, death from lung cancer, and death from any cause. At entry, subjects had an age range of 45 to 59 years; men numbered 186 and women 40. Histologically proven lung cancer developed in 9 cases and in 2 controls, all men. The rate of development of lung cancer was significantly different in the two groups (p = 0.024): the 10-year cumulative percentage was 8.8% for cases and 2.0% for controls. Overall 10-year survival was estimated to be 74.0% for cases and 91.1% for controls (p less than 0.001). http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of internal medicine Pubmed

Higher risk of lung cancer in chronic obstructive pulmonary disease. A prospective, matched, controlled study.

Annals of internal medicine , Volume 105 (4): -495 – Oct 10, 1986

Higher risk of lung cancer in chronic obstructive pulmonary disease. A prospective, matched, controlled study.


Abstract

To assess the risk of lung cancer in patients with chronic obstructive pulmonary disease, we matched, on the basis of age, sex, occupation, and smoking history, 113 persons ("cases") who had a forced expiratory volume in 1 second (FEV1) of 70% or less of predicted normal with 113 control persons who had an FEV1 of 85% or more. All persons were observed from 1973-74 through 1984 for a diagnosis of lung cancer, death from lung cancer, and death from any cause. At entry, subjects had an age range of 45 to 59 years; men numbered 186 and women 40. Histologically proven lung cancer developed in 9 cases and in 2 controls, all men. The rate of development of lung cancer was significantly different in the two groups (p = 0.024): the 10-year cumulative percentage was 8.8% for cases and 2.0% for controls. Overall 10-year survival was estimated to be 74.0% for cases and 91.1% for controls (p less than 0.001).

Loading next page...
 
/lp/pubmed/higher-risk-of-lung-cancer-in-chronic-obstructive-pulmonary-disease-a-7xz0Zn8Avy

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

ISSN
0003-4819
DOI
10.7326/0003-4819-105-4-503
pmid
3752756

Abstract

To assess the risk of lung cancer in patients with chronic obstructive pulmonary disease, we matched, on the basis of age, sex, occupation, and smoking history, 113 persons ("cases") who had a forced expiratory volume in 1 second (FEV1) of 70% or less of predicted normal with 113 control persons who had an FEV1 of 85% or more. All persons were observed from 1973-74 through 1984 for a diagnosis of lung cancer, death from lung cancer, and death from any cause. At entry, subjects had an age range of 45 to 59 years; men numbered 186 and women 40. Histologically proven lung cancer developed in 9 cases and in 2 controls, all men. The rate of development of lung cancer was significantly different in the two groups (p = 0.024): the 10-year cumulative percentage was 8.8% for cases and 2.0% for controls. Overall 10-year survival was estimated to be 74.0% for cases and 91.1% for controls (p less than 0.001).

Journal

Annals of internal medicinePubmed

Published: Oct 10, 1986

There are no references for this article.