Get 20M+ Full-Text Papers For Less Than $1.50/day. Subscribe now for You or Your Team.

Learn More →

Multiple approach to the exploration of genotype-phenotype correlations in familial adenomatous polyposis.

Multiple approach to the exploration of genotype-phenotype correlations in familial adenomatous... Familial adenomatous polyposis (FAP), caused by a mutation in the APC gene, is a colorectal cancer predisposition syndrome associated with several other clinical conditions. The severity of the FAP is related to the position of the inherited mutation in the APC gene. We analyzed a large series of FAP patients to identify associations among major clinical manifestations and to correlate the mutation site with specific disease manifestations. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of clinical oncology : official journal of the American Society of Clinical Oncology Pubmed

Multiple approach to the exploration of genotype-phenotype correlations in familial adenomatous polyposis.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology , Volume 21 (9): 10 – May 20, 2003

Multiple approach to the exploration of genotype-phenotype correlations in familial adenomatous polyposis.


Abstract

Familial adenomatous polyposis (FAP), caused by a mutation in the APC gene, is a colorectal cancer predisposition syndrome associated with several other clinical conditions. The severity of the FAP is related to the position of the inherited mutation in the APC gene. We analyzed a large series of FAP patients to identify associations among major clinical manifestations and to correlate the mutation site with specific disease manifestations.

Loading next page...
 
/lp/pubmed/multiple-approach-to-the-exploration-of-genotype-phenotype-umMNbE0RXe

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

ISSN
0732-183X
DOI
10.1200/JCO.2003.09.118
pmid
12721244

Abstract

Familial adenomatous polyposis (FAP), caused by a mutation in the APC gene, is a colorectal cancer predisposition syndrome associated with several other clinical conditions. The severity of the FAP is related to the position of the inherited mutation in the APC gene. We analyzed a large series of FAP patients to identify associations among major clinical manifestations and to correlate the mutation site with specific disease manifestations.

Journal

Journal of clinical oncology : official journal of the American Society of Clinical OncologyPubmed

Published: May 20, 2003

There are no references for this article.