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Oestrogen supplementation, mainly diethylstilbestrol, for preventing miscarriages and other adverse pregnancy outcomes.

Oestrogen supplementation, mainly diethylstilbestrol, for preventing miscarriages and other... Laboratory evidence in the 1940s demonstrated a positive role of placental hormones in the continuation of pregnancy. It was suggested that diethylstilbestrol was the oestrogen of choice for prevention of miscarriages. Observational studies were carried out with apparently positive results, on which clinical practice was based. This led to a worldwide usage of diethylstilbestrol despite controlled studies with contrary findings. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cochrane Database of Systematic Reviews Pubmed

Oestrogen supplementation, mainly diethylstilbestrol, for preventing miscarriages and other adverse pregnancy outcomes.

Cochrane Database of Systematic Reviews , Volume (3): -4352999999 – Sep 25, 2003

Oestrogen supplementation, mainly diethylstilbestrol, for preventing miscarriages and other adverse pregnancy outcomes.


Abstract

Laboratory evidence in the 1940s demonstrated a positive role of placental hormones in the continuation of pregnancy. It was suggested that diethylstilbestrol was the oestrogen of choice for prevention of miscarriages. Observational studies were carried out with apparently positive results, on which clinical practice was based. This led to a worldwide usage of diethylstilbestrol despite controlled studies with contrary findings.

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ISSN
1465-1858
eISSN
1469-493X
DOI
10.1002/14651858.CD004353
pmid
12918007
Publisher site
See Article on Publisher Site

Abstract

Laboratory evidence in the 1940s demonstrated a positive role of placental hormones in the continuation of pregnancy. It was suggested that diethylstilbestrol was the oestrogen of choice for prevention of miscarriages. Observational studies were carried out with apparently positive results, on which clinical practice was based. This led to a worldwide usage of diethylstilbestrol despite controlled studies with contrary findings.

Journal

Cochrane Database of Systematic ReviewsPubmed

Published: Sep 25, 2003

There are no references for this article.