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[Recent advances in the genetics of schizophrenia and the practical implications of the results].

[Recent advances in the genetics of schizophrenia and the practical implications of the results]. Research targeting the genetic background of schizophrenia has expanded our knowledge substantially about genes and possible pathophysiological processes playing a role in the disorder. In addition to earlier approaches, new genetic methods have been developed which offer new insight. In this review we make an attempt to summarize the findings of earlier genetic research, as well as to interpret newly emerging results that help the development of pathophysiologically oriented models of schizophrenia. We argue that besides genetic research, findings on cognitive function and of imaging studies, as well as gene-expression analyses and pharmacogenetic studies must be interpreted to reach a better understanding of the complex phenomena in schizophrenia. Synthesis of data from the different areas allows speculation about future research and practical implications. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychiatria Hungarica : A Magyar Pszichiatriai Tarsasag tudomanyos folyoirata Pubmed

[Recent advances in the genetics of schizophrenia and the practical implications of the results].

Psychiatria Hungarica : A Magyar Pszichiatriai Tarsasag tudomanyos folyoirata , Volume 23 (3): 14 – Nov 18, 2008

[Recent advances in the genetics of schizophrenia and the practical implications of the results].


Abstract

Research targeting the genetic background of schizophrenia has expanded our knowledge substantially about genes and possible pathophysiological processes playing a role in the disorder. In addition to earlier approaches, new genetic methods have been developed which offer new insight. In this review we make an attempt to summarize the findings of earlier genetic research, as well as to interpret newly emerging results that help the development of pathophysiologically oriented models of schizophrenia. We argue that besides genetic research, findings on cognitive function and of imaging studies, as well as gene-expression analyses and pharmacogenetic studies must be interpreted to reach a better understanding of the complex phenomena in schizophrenia. Synthesis of data from the different areas allows speculation about future research and practical implications.

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ISSN
0237-7896
pmid
18956622

Abstract

Research targeting the genetic background of schizophrenia has expanded our knowledge substantially about genes and possible pathophysiological processes playing a role in the disorder. In addition to earlier approaches, new genetic methods have been developed which offer new insight. In this review we make an attempt to summarize the findings of earlier genetic research, as well as to interpret newly emerging results that help the development of pathophysiologically oriented models of schizophrenia. We argue that besides genetic research, findings on cognitive function and of imaging studies, as well as gene-expression analyses and pharmacogenetic studies must be interpreted to reach a better understanding of the complex phenomena in schizophrenia. Synthesis of data from the different areas allows speculation about future research and practical implications.

Journal

Psychiatria Hungarica : A Magyar Pszichiatriai Tarsasag tudomanyos folyoirataPubmed

Published: Nov 18, 2008

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