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Wounds: an overview of the role of oxygen.

Wounds: an overview of the role of oxygen. We sought to review the role of oxygen in wound healing, with an emphasis on the role tissue oximetry has played in clinical advances in the care of patients with wounds. Oxygen is required for wound healing. Hypoxia sufficient to impair healing is common in wounds, frequently resulting from sympathetically induced vasoconstriction. Correction or prevention of vasoconstriction, as well as provision of increased inspired oxygen in well-perfused patients, has been shown in randomized, controlled clinical trials to improve wound outcomes. Our understanding of the role of oxygen in wound healing has been fueled by tissue oximetry. Advances in technology will lead to further advances in the management of patients with wounds. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Antioxidants & redox signaling Pubmed

Wounds: an overview of the role of oxygen.

Antioxidants & redox signaling , Volume 9 (8): -1090 – Sep 14, 2007

Wounds: an overview of the role of oxygen.


Abstract

We sought to review the role of oxygen in wound healing, with an emphasis on the role tissue oximetry has played in clinical advances in the care of patients with wounds. Oxygen is required for wound healing. Hypoxia sufficient to impair healing is common in wounds, frequently resulting from sympathetically induced vasoconstriction. Correction or prevention of vasoconstriction, as well as provision of increased inspired oxygen in well-perfused patients, has been shown in randomized, controlled clinical trials to improve wound outcomes. Our understanding of the role of oxygen in wound healing has been fueled by tissue oximetry. Advances in technology will lead to further advances in the management of patients with wounds.

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ISSN
1523-0864
DOI
10.1089/ars.2007.1641
pmid
17536961

Abstract

We sought to review the role of oxygen in wound healing, with an emphasis on the role tissue oximetry has played in clinical advances in the care of patients with wounds. Oxygen is required for wound healing. Hypoxia sufficient to impair healing is common in wounds, frequently resulting from sympathetically induced vasoconstriction. Correction or prevention of vasoconstriction, as well as provision of increased inspired oxygen in well-perfused patients, has been shown in randomized, controlled clinical trials to improve wound outcomes. Our understanding of the role of oxygen in wound healing has been fueled by tissue oximetry. Advances in technology will lead to further advances in the management of patients with wounds.

Journal

Antioxidants & redox signalingPubmed

Published: Sep 14, 2007

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