Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Disseminated Cutaneous Varicella Zoster Virus Infections During Infliximab Therapy for Crohn’s Disease: Case Report of Two Pediatric Patients at One Institution

Disseminated Cutaneous Varicella Zoster Virus Infections During Infliximab Therapy for Crohn’s... Brief Reports Clinical Pediatrics 50(6) 559 –561 Disseminated Cutaneous © The Author(s) 2011 Reprints and permission: http://www. sagepub.com/journalsPermissions.nav Varicella Zoster Virus Infections DOI: 10.1177/0009922810380452 http://cpj.sagepub.com During Infliximab Therapy for Crohn’s Disease: Case Report of Two Pediatric Patients at One Institution 1,2 1,2 Anjali N. Kunz, MD , and Michael Rajnik, MD for a clinical suspicion of varicella infection. At this Introduction visit, she reported a known exposure to a classmate who Infliximab is a monoclonal antibody against tumor necro- developed primary varicella infection 1 week ago. She sis factor-a (TNF-a) that has been approved for the had no prior history of documented VZV infection, and treatment of rheumatoid arthritis and Crohn’s disease. her immunizations were up to date to include varicella It is used in steroid-sparing regimens for patients who vaccination during early childhood. Despite 2 days of have had an inadequate response to conventional ther- valacyclovir therapy, her rash progressed to involve her apy. There are a number of studies that have shown an upper and lower extremities. However, she continued to increased risk of infections with bacteria, fungi, myco- remain afebrile with no associated systemic symptoms. bacterium, and more recently, chronic viral infections She was admitted to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Pediatrics SAGE

Disseminated Cutaneous Varicella Zoster Virus Infections During Infliximab Therapy for Crohn’s Disease: Case Report of Two Pediatric Patients at One Institution

Clinical Pediatrics , Volume 50 (6): 3 – Jun 1, 2011

Loading next page...
 
/lp/sage/disseminated-cutaneous-varicella-zoster-virus-infections-during-jp8e8wNPky

References (5)

Publisher
SAGE
Copyright
© The Author(s) 2011
ISSN
0009-9228
eISSN
1938-2707
DOI
10.1177/0009922810380452
pmid
20837619
Publisher site
See Article on Publisher Site

Abstract

Brief Reports Clinical Pediatrics 50(6) 559 –561 Disseminated Cutaneous © The Author(s) 2011 Reprints and permission: http://www. sagepub.com/journalsPermissions.nav Varicella Zoster Virus Infections DOI: 10.1177/0009922810380452 http://cpj.sagepub.com During Infliximab Therapy for Crohn’s Disease: Case Report of Two Pediatric Patients at One Institution 1,2 1,2 Anjali N. Kunz, MD , and Michael Rajnik, MD for a clinical suspicion of varicella infection. At this Introduction visit, she reported a known exposure to a classmate who Infliximab is a monoclonal antibody against tumor necro- developed primary varicella infection 1 week ago. She sis factor-a (TNF-a) that has been approved for the had no prior history of documented VZV infection, and treatment of rheumatoid arthritis and Crohn’s disease. her immunizations were up to date to include varicella It is used in steroid-sparing regimens for patients who vaccination during early childhood. Despite 2 days of have had an inadequate response to conventional ther- valacyclovir therapy, her rash progressed to involve her apy. There are a number of studies that have shown an upper and lower extremities. However, she continued to increased risk of infections with bacteria, fungi, myco- remain afebrile with no associated systemic symptoms. bacterium, and more recently, chronic viral infections She was admitted to

Journal

Clinical PediatricsSAGE

Published: Jun 1, 2011

There are no references for this article.