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Progressive Tumefactive Fibroinflammatory Lesion of the Infratemporal Fossa Treated by Radiation Therapy

Progressive Tumefactive Fibroinflammatory Lesion of the Infratemporal Fossa Treated by Radiation... Abstract Tumefactive fibroinflammatory lesion (TFIL) is a rare benign tumor in the head and neck region. We present a case of a 40-year-old female with a benign but progressive lesion of the infratemporal fossa, which was diagnosed as TFIL. Patient responded briefly to a course of steroid treatment but eventually showed progression and was unresponsive to further steroids. She was then treated with external beam radiation to a dose of 60 Gy in 30 fractions. After radiation a slow, gradual decrease in tumor size was noted over the course of years and she is free of disease after more than 11 years of follow-up. The major long-term side effect this patient developed was an expected unilateral radiation-induced retinopathy, due to the close proximity of the lesion to the orbit. The dilemma of treatment of benign disease with radiation with potential long-term complications is discussed and a review of the literature on TFIL is presented. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Rare Tumors SAGE

Progressive Tumefactive Fibroinflammatory Lesion of the Infratemporal Fossa Treated by Radiation Therapy

Progressive Tumefactive Fibroinflammatory Lesion of the Infratemporal Fossa Treated by Radiation Therapy

Rare Tumors , Volume OnlineFirst: 1 – Mar 1, 2012

Abstract

Abstract Tumefactive fibroinflammatory lesion (TFIL) is a rare benign tumor in the head and neck region. We present a case of a 40-year-old female with a benign but progressive lesion of the infratemporal fossa, which was diagnosed as TFIL. Patient responded briefly to a course of steroid treatment but eventually showed progression and was unresponsive to further steroids. She was then treated with external beam radiation to a dose of 60 Gy in 30 fractions. After radiation a slow, gradual decrease in tumor size was noted over the course of years and she is free of disease after more than 11 years of follow-up. The major long-term side effect this patient developed was an expected unilateral radiation-induced retinopathy, due to the close proximity of the lesion to the orbit. The dilemma of treatment of benign disease with radiation with potential long-term complications is discussed and a review of the literature on TFIL is presented.

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References (35)

Publisher
SAGE
Copyright
© 2012 SAGE Publications.
ISSN
2036-3613
eISSN
2036-3613
DOI
10.4081/rt.2012.e12
Publisher site
See Article on Publisher Site

Abstract

Abstract Tumefactive fibroinflammatory lesion (TFIL) is a rare benign tumor in the head and neck region. We present a case of a 40-year-old female with a benign but progressive lesion of the infratemporal fossa, which was diagnosed as TFIL. Patient responded briefly to a course of steroid treatment but eventually showed progression and was unresponsive to further steroids. She was then treated with external beam radiation to a dose of 60 Gy in 30 fractions. After radiation a slow, gradual decrease in tumor size was noted over the course of years and she is free of disease after more than 11 years of follow-up. The major long-term side effect this patient developed was an expected unilateral radiation-induced retinopathy, due to the close proximity of the lesion to the orbit. The dilemma of treatment of benign disease with radiation with potential long-term complications is discussed and a review of the literature on TFIL is presented.

Journal

Rare TumorsSAGE

Published: Mar 1, 2012

Keywords: tumefactive; fibroinflammatory; inflammatory; radiation therapy

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