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April Armstrong, J. Koning, Simon Rowse, H. Tan, C. Mamolo, M. Kaur (2016)
Under-Treatment of Patients with Moderate to Severe Psoriasis in the United States: Analysis of Medication Usage with Health Plan DataDermatology and Therapy, 7
F. Ricceri, F. Bardazzi, Andrea Chiricozzi, P. Dapavo, Francesca Ferrara, C. Mugheddu, Marco Romanelli, Franco Rongioletti, F. Prignano (2018)
Elderly psoriatic patients under biological therapies: an Italian experienceJournal of the European Academy of Dermatology and Venereology, 33
J. Wong, J. Koo (2012)
The Safety of Systemic Treatments That Can Be Used for Geriatric Psoriasis Patients: A ReviewDermatology Research and Practice, 2012
E. Montecino-Rodriguez, B. Berent-Maoz, K. Dorshkind (2013)
Causes, consequences, and reversal of immune system aging.The Journal of clinical investigation, 123 3
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F. Sampogna, M. Chren, C. Melchi, P. Pasquini, S. Tabolli, D. Abeni (2006)
Age, gender, quality of life and psychological distress in patients hospitalized with psoriasisBritish Journal of Dermatology, 154
Background:Elderly patients have worse skin related quality of life regardless of psoriasis severity. Despite this, there may be risks to starting systemic immunosuppressant therapy, a mainstay for moderate to severe psoriasis, in elderly patients.Objective:We assessed how age relates to treatment intensity for psoriasis. We defined treatment intensity as a continuous scale with a value of 0 indicating no treatment, 1 indicating topical treatment only, and 2 through 4 indicating progressive degrees of systemic treatment.Methods:We assessed the National Ambulatory Medical Care Survey from 1997 to 2016 to determine if treatment intensity for psoriasis was related to a patient’s age.Results:Between 1997 to 2006, a 1-year increase in age was not associated with a change in treatment intensity score for the younger (p = .4) and older (p = .8) age groups. Between 2007 to 2016, a 1-year increase in age was associated with a .01 (95% confidence interval .005, .02) decrease in the treatment intensity score (p = .003) for patients aged 52 or older. When controlling for sex and race, a 1-year increase in age was associated with a decrease of .01 (.02, .005) in the treatment intensity score (p = .005). There was no association with those who were younger than 52 (p = .5).Discussion:Physicians provide less intense treatments for elderly patients with psoriasis. This effect has appeared in the last decade. It remains unknown if physicians are being cautious with more intense treatments in elderly patients or if they are unintentionally undertreating this population.
Journal of Psoriasis and Psoriatic Arthritis – SAGE
Published: Apr 1, 2021
Keywords: skin; dermatology; quality of life; treatment; biologic; systemic
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