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Primary non‑Hodgkin lymphoma of the extra‑hepatic bile duct: A case report

Primary non‑Hodgkin lymphoma of the extra‑hepatic bile duct: A case report Lymphoma is known to be a systemic lymphoproliferative malignancy, which is divided into two subtypes: Hodgkin lymphoma and non‑Hodgkin lymphoma. Non‑Hodgkin lymphoma originates from nodal and extranodal sites. In the staging of non‑Hodgkin lymphoma, the liver is implicated in 40% of cases; however, primary liver non‑Hodgkin lymphoma represents <1% of all non‑Hodgkin lymphoma cases. Because of its rarity, it is not usually considered in the differential diagnosis of patients that present with jaundice. Since the first case of primary non‑Hodgkin lymphoma of the extra‑hepatic bile ducts was presented, only 42 similar cases have been reported in the English literature. The present case report describes a rare case of non‑Hodgkin lymphoma of the common hepatic duct, which presented with obstructive jaundice and represented a complex differential diagnostic issue. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Molecular and Clinical Oncology Spandidos Publications

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Publisher
Spandidos Publications
Copyright
Copyright © 2022 Spandidos Publications
ISSN
2049-9450
DOI
10.3892/mco.2022.2548

Abstract

Lymphoma is known to be a systemic lymphoproliferative malignancy, which is divided into two subtypes: Hodgkin lymphoma and non‑Hodgkin lymphoma. Non‑Hodgkin lymphoma originates from nodal and extranodal sites. In the staging of non‑Hodgkin lymphoma, the liver is implicated in 40% of cases; however, primary liver non‑Hodgkin lymphoma represents <1% of all non‑Hodgkin lymphoma cases. Because of its rarity, it is not usually considered in the differential diagnosis of patients that present with jaundice. Since the first case of primary non‑Hodgkin lymphoma of the extra‑hepatic bile ducts was presented, only 42 similar cases have been reported in the English literature. The present case report describes a rare case of non‑Hodgkin lymphoma of the common hepatic duct, which presented with obstructive jaundice and represented a complex differential diagnostic issue.

Journal

Molecular and Clinical OncologySpandidos Publications

Published: Jul 4, 2022

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