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Targeted Oncology (2020) 15:7–9 https://doi.org/10.1007/s11523-020-00700-6 MEE TING REPOR T 2019 San Antonio Breast Cancer Symposium: San Antonio, TX, USA, 10–14 December 2019 Martin Chopra Published online: 25 January 2020 © Springer Nature Switzerland AG 2020 The San Antonio Breast Cancer Symposium (SABCS) pro- 184 patients across the two parts of the trial had received vides state-of-the-art information on the experimental biol- this dose. ogy, etiology, prevention, diagnosis, and therapy of breast The majority of the patients were white (55%), and cancer and premalignant breast disease, to an international 38% were Asian, and the median age was 55 years (range audience of well over 7500 academic and private physicians 28–96 years). Fifty-three percent were hormone receptor and researchers. (HR)-positive and 45% were HR-negative. At baseline, the The results of numerous important clinical trials were median number of prior treatment regimens was 6 (range showcased at this year’s symposium. Here, I present a brief 2–27), including trastuzumab (100%), T-DM1 (100%), per- summary of some of the highlights of the meeting, focussing tuzumab (66%), and other HER2-targeted regimens (54%). on molecularly targeted approaches, including two novel The objective response rate (ORR) was 60.9% (95% CI later-line therapeutic agents that target HER2, and several 53.4–68.0), including
Targeted Oncology – Springer Journals
Published: Feb 25, 2020
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