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A Case-Based Guide to Clinical EndocrinologyDifferentiation of Primary Hyperparathyroidism for Familial Benign Hypocalciuric Hypercalcemia

A Case-Based Guide to Clinical Endocrinology: Differentiation of Primary Hyperparathyroidism for... Chapter 18 Differentiation of Primary Hyperparathyroidism for Familial Benign Hypocalciuric Hypercalcemia Ebaa Al Ozairi Case Presentation An 84-year-old Caucasian woman was discovered on routine testing to have raised serum calcium of 2.63 mmol/L (10.52 mg/dL). No symptoms of thirst, heartburn, indigestion, bone pain, or constipation were elicited. She denied mood changes or a history of kidney stones. Dietary history revealed a normal mixed diet, including daily dairy products. She smoked 10 cigarettes daily. Her past medical history was significant for a squamous cell carcinoma of the vulva, treated 10 years previously with a radical vulvectomy and external beam radiotherapy. Medications included furosemide 20 mg daily, naproxen 250 mg twice daily, and amitriptyline 25 mg at night. Family history was negative. A physical examination was unremarkable. Her laboratory data were as follows (with reference ranges): Total serum calcium = 2.63 mmol/L (2.12–2.60) Albumin = 37 g/L (34–50) Ionized calcium = 1.38 mmol/L (1.19–1.37) Phosphorus = 1.00 mmol/L (0.8–1.44) Magnesium = 0.98 mmol/L (0.7–1.00) Alkaline phosphatase = 65 U/L (35–120) Parathyroid hormone (PTH) = 111 ng/L (10–65) Serum creatinine= 125 mol/L (70–145) Thyroid-stimulating hormone (TSH) = 0.95 mIU/L (0.3–4.7) 24-hour urine Ca = 2.6 mmol/24 h (2.5–7.5) 24-hour urine Cr = http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Case-Based Guide to Clinical EndocrinologyDifferentiation of Primary Hyperparathyroidism for Familial Benign Hypocalciuric Hypercalcemia

Part of the Contemporary Endocrinology™ Book Series
Editors: Davies, Terry F.
Ozairi, Ebaa Al
A Case-Based Guide to Clinical Endocrinology — Jan 1, 2008
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Publisher
Humana Press
Copyright
© Humana Press,Totowa, NJ 2008
ISBN
978-1-58829-815-7
Pages
179 –182
DOI
10.1007/978-1-60327-103-5_18
Publisher site
See Chapter on Publisher Site

Abstract

Chapter 18 Differentiation of Primary Hyperparathyroidism for Familial Benign Hypocalciuric Hypercalcemia Ebaa Al Ozairi Case Presentation An 84-year-old Caucasian woman was discovered on routine testing to have raised serum calcium of 2.63 mmol/L (10.52 mg/dL). No symptoms of thirst, heartburn, indigestion, bone pain, or constipation were elicited. She denied mood changes or a history of kidney stones. Dietary history revealed a normal mixed diet, including daily dairy products. She smoked 10 cigarettes daily. Her past medical history was significant for a squamous cell carcinoma of the vulva, treated 10 years previously with a radical vulvectomy and external beam radiotherapy. Medications included furosemide 20 mg daily, naproxen 250 mg twice daily, and amitriptyline 25 mg at night. Family history was negative. A physical examination was unremarkable. Her laboratory data were as follows (with reference ranges): Total serum calcium = 2.63 mmol/L (2.12–2.60) Albumin = 37 g/L (34–50) Ionized calcium = 1.38 mmol/L (1.19–1.37) Phosphorus = 1.00 mmol/L (0.8–1.44) Magnesium = 0.98 mmol/L (0.7–1.00) Alkaline phosphatase = 65 U/L (35–120) Parathyroid hormone (PTH) = 111 ng/L (10–65) Serum creatinine= 125 mol/L (70–145) Thyroid-stimulating hormone (TSH) = 0.95 mIU/L (0.3–4.7) 24-hour urine Ca = 2.6 mmol/24 h (2.5–7.5) 24-hour urine Cr =

Published: Jan 1, 2008

Keywords: Primary Hyperparathyroidism; Parathyroid Carcinoma; Band Keratopathy; Autoimmune Polyendocrine Syndrome; Mild Hypercalcemia

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