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A Case-Based Guide to Clinical EndocrinologyFollicular Thyroid Carcinoma with Pulmonary and Osseous Metastases

A Case-Based Guide to Clinical Endocrinology: Follicular Thyroid Carcinoma with Pulmonary and... Chapter 14 Follicular Thyroid Carcinoma with Pulmonary and Osseous Metastases Jason A. Wexler and Kenneth D. Burman Objectives 1. Discuss the appropriate screening modalities for osseous metastases in the setting of follicular thyroid carcinoma. 2. Discuss the role of biopsy in the evaluation of osseous metastases. 3. Discuss the role and efficacy of I therapy in follicular thyroid carcinoma with osseous metastases. 4. Discuss the efficacy and side effects of intravenous bisphosphonates in the treat- ment of osseous metastases. 5. Discuss the role and efficacy of novel therapies (i.e., radiofrequency ablation, external beam radiation, and cryotherapy) in the treatment of osseous metastases. 6. Discuss the appropriate monitoring strategies for patients with follicular thyroid carcinoma and osseous metastases. Case Presentation A 72-year-old man underwent a total thyroidectomy in July 1989 for Hu ¨ rthle cell thyroid carcinoma, which invaded lymphatic and venous channels at distant sites from the mass. A cervical lymph node also revealed metastatic involvement. He subsequently received iodine 131 ( I) 168.7 mCi in August 1990, and a postther- apy whole-body scan was negative for distant metastases, although there was neck bed uptake. In November 1991, he received an additional 105 mCi 131–1 for Per- sistent thyroglobulin http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Case-Based Guide to Clinical EndocrinologyFollicular Thyroid Carcinoma with Pulmonary and Osseous Metastases

Part of the Contemporary Endocrinology™ Book Series
Editors: Davies, Terry F.
Wexler, Jason A.; Burman, Kenneth D.
A Case-Based Guide to Clinical Endocrinology — Jan 1, 2008
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13 pages

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Publisher
Humana Press
Copyright
© Humana Press,Totowa, NJ 2008
ISBN
978-1-58829-815-7
Pages
139 –152
DOI
10.1007/978-1-60327-103-5_14
Publisher site
See Chapter on Publisher Site

Abstract

Chapter 14 Follicular Thyroid Carcinoma with Pulmonary and Osseous Metastases Jason A. Wexler and Kenneth D. Burman Objectives 1. Discuss the appropriate screening modalities for osseous metastases in the setting of follicular thyroid carcinoma. 2. Discuss the role of biopsy in the evaluation of osseous metastases. 3. Discuss the role and efficacy of I therapy in follicular thyroid carcinoma with osseous metastases. 4. Discuss the efficacy and side effects of intravenous bisphosphonates in the treat- ment of osseous metastases. 5. Discuss the role and efficacy of novel therapies (i.e., radiofrequency ablation, external beam radiation, and cryotherapy) in the treatment of osseous metastases. 6. Discuss the appropriate monitoring strategies for patients with follicular thyroid carcinoma and osseous metastases. Case Presentation A 72-year-old man underwent a total thyroidectomy in July 1989 for Hu ¨ rthle cell thyroid carcinoma, which invaded lymphatic and venous channels at distant sites from the mass. A cervical lymph node also revealed metastatic involvement. He subsequently received iodine 131 ( I) 168.7 mCi in August 1990, and a postther- apy whole-body scan was negative for distant metastases, although there was neck bed uptake. In November 1991, he received an additional 105 mCi 131–1 for Per- sistent thyroglobulin

Published: Jan 1, 2008

Keywords: Positron Emission Tomography; Thyroid Cancer; Bone Metastasis; Standardize Uptake Value; Zoledronic Acid

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