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A Case-Based Guide to Clinical EndocrinologyPapillary Thyroid Cancer

A Case-Based Guide to Clinical Endocrinology: Papillary Thyroid Cancer Chapter 11 Nicole Ehrhardt and Victor Bernet Objectives 1. To understand the presentation and diagnosis of papillary thyroid cancer (PTC) 2. To review the risk factors for recurrence and mortality in PTC 3. To discuss the initial surgical recommendations for PTC 4. To examine the clinical indications for radioactive iodine for PTC 5. To review the appropriate long-term management, surveillance, and follow-up for patients with PTC Case Presentation A 44-year-old woman with chronic neck pain was incidentally found to have a left thyroid nodule on magnetic resonance imaging (MRI) of the neck. Her medical history was otherwise unremarkable. Thyroid ultrasound revealed a lone 1.1-cm left thyroid nodule with prominent intranodular vasculature flow, irregular borders, and microcalcifications. Endocrinology was then consulted. Free thyroxine (FT )and thyroid-stimulating hormone (TSH) were in the normal range. No family history of thyroid disease or cancer was noted, and the patient had no radiation exposure history. The physical examination was unremarkable, including no palpable thyroid nod- ules or lymph nodes in the neck. Ultrasound-guided fine-needle aspiration of the nodule was performed, and the cytology report noted scant colloid, crowded groups of follicular cells with distinct nuclear grooving, and overall consistent with pap- illary thyroid cancer. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Case-Based Guide to Clinical EndocrinologyPapillary Thyroid Cancer

Part of the Contemporary Endocrinology™ Book Series
Editors: Davies, Terry F.

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Publisher
Humana Press
Copyright
© Humana Press,Totowa, NJ 2008
ISBN
978-1-58829-815-7
Pages
109 –119
DOI
10.1007/978-1-60327-103-5_11
Publisher site
See Chapter on Publisher Site

Abstract

Chapter 11 Nicole Ehrhardt and Victor Bernet Objectives 1. To understand the presentation and diagnosis of papillary thyroid cancer (PTC) 2. To review the risk factors for recurrence and mortality in PTC 3. To discuss the initial surgical recommendations for PTC 4. To examine the clinical indications for radioactive iodine for PTC 5. To review the appropriate long-term management, surveillance, and follow-up for patients with PTC Case Presentation A 44-year-old woman with chronic neck pain was incidentally found to have a left thyroid nodule on magnetic resonance imaging (MRI) of the neck. Her medical history was otherwise unremarkable. Thyroid ultrasound revealed a lone 1.1-cm left thyroid nodule with prominent intranodular vasculature flow, irregular borders, and microcalcifications. Endocrinology was then consulted. Free thyroxine (FT )and thyroid-stimulating hormone (TSH) were in the normal range. No family history of thyroid disease or cancer was noted, and the patient had no radiation exposure history. The physical examination was unremarkable, including no palpable thyroid nod- ules or lymph nodes in the neck. Ultrasound-guided fine-needle aspiration of the nodule was performed, and the cytology report noted scant colloid, crowded groups of follicular cells with distinct nuclear grooving, and overall consistent with pap- illary thyroid cancer.

Published: Jan 1, 2008

Keywords: Thyroid Cancer; Thyroid Carcinoma; Papillary Thyroid Carcinoma; Thyroid Nodule; Papillary Thyroid

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