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A Case-Based Guide to Clinical EndocrinologySubacute (De Quervain’s) Thyroiditis

A Case-Based Guide to Clinical Endocrinology: Subacute (De Quervain’s) Thyroiditis Chapter 7 Paul Aoun and David S. Cooper Objectives Subacute thyroiditis is a relatively unusual inflammatory condition of the thyroid that likely has a viral etiology. We report the case of a 40-year-old woman with typical signs and symptoms of subacute thyroiditis. We then discuss the important clinical aspects of the disease, examine the diagnostic strategies, and review the pharmacologic management. Case Presentation Ms. A.S. is a 40-year-old woman who presented to her primary care physician with a 2-week history of malaise, fever, and palpitations. She also had noted a lump in the right anterior neck. Thyroid function tests had shown mild hyperthyroidism, and the patient was referred for evaluation of a possible “hot” nodule. On close questioning, the patient had had an upper respiratory infection the previous month. She then developed nightly fevers of 104 F, associated with drenching sweats and a 10-pound weight loss. She also had noted a tender swelling in the right neck for approximately 2 weeks, with the pain radiating to her right ear. There was no previous history of thyroid disease, family history of thyroid disease, or history of head and neck irradiation. The patient’s physical examination was significant for pulse 100 beats http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Case-Based Guide to Clinical EndocrinologySubacute (De Quervain’s) Thyroiditis

Part of the Contemporary Endocrinology™ Book Series
Editors: Davies, Terry F.
Springer Journals — Jan 1, 2008

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Publisher
Humana Press
Copyright
© Humana Press,Totowa, NJ 2008
ISBN
978-1-58829-815-7
Pages
67 –72
DOI
10.1007/978-1-60327-103-5_7
Publisher site
See Chapter on Publisher Site

Abstract

Chapter 7 Paul Aoun and David S. Cooper Objectives Subacute thyroiditis is a relatively unusual inflammatory condition of the thyroid that likely has a viral etiology. We report the case of a 40-year-old woman with typical signs and symptoms of subacute thyroiditis. We then discuss the important clinical aspects of the disease, examine the diagnostic strategies, and review the pharmacologic management. Case Presentation Ms. A.S. is a 40-year-old woman who presented to her primary care physician with a 2-week history of malaise, fever, and palpitations. She also had noted a lump in the right anterior neck. Thyroid function tests had shown mild hyperthyroidism, and the patient was referred for evaluation of a possible “hot” nodule. On close questioning, the patient had had an upper respiratory infection the previous month. She then developed nightly fevers of 104 F, associated with drenching sweats and a 10-pound weight loss. She also had noted a tender swelling in the right neck for approximately 2 weeks, with the pain radiating to her right ear. There was no previous history of thyroid disease, family history of thyroid disease, or history of head and neck irradiation. The patient’s physical examination was significant for pulse 100 beats

Published: Jan 1, 2008

Keywords: Thyroid Nodule; Multinucleated Giant Cell; Glucocorticoid Therapy; Multinodular Goiter; Elevated Erythrocyte Sedimentation Rate

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