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A Comprehensive Guide to Core Needle Biopsies of the Breast Intraductal Proliferations (DCIS, ADH, and UDH)

A Comprehensive Guide to Core Needle Biopsies of the Breast : Intraductal Proliferations (DCIS,... [The diagnostic evaluation of intraductal proliferations, including ductal carcinoma in situ (DCIS), atypical ductal hyperplasia (ADH), and usual ductal hyperplasia (UDH) is one of the most common diagnostic challenges in breast pathology. While proliferations on the ends of this diagnostic spectrum (high-grade DCIS and classic usual ductal hyperplasia) are usually more straightforward to classify, the distinction between low-grade DCIS and ADH can be particularly problematic. An understanding of the biology of these lesions reveals more about their complexity and which lesions are more closely related to each other. When evaluating intraductal proliferations on core needle biopsy samples, pathologists should understand the critical aspects of establishing these diagnoses as well as their clinical impact. This chapter will review practical approaches to the diagnosis of intraductal proliferative lesions on core biopsy as well as some of their diagnostic challenges and clinical implications.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Comprehensive Guide to Core Needle Biopsies of the Breast Intraductal Proliferations (DCIS, ADH, and UDH)

Editors: Shin, Sandra J.
Allison, Kimberly H.; Jensen, Kristin C.
Springer Journals — Sep 17, 2016
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38 pages

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Publisher
Springer International Publishing
Copyright
© Springer International Publishing Switzerland 2016
ISBN
978-3-319-26289-5
Pages
337 –375
DOI
10.1007/978-3-319-26291-8_9
Publisher site
See Chapter on Publisher Site

Abstract

[The diagnostic evaluation of intraductal proliferations, including ductal carcinoma in situ (DCIS), atypical ductal hyperplasia (ADH), and usual ductal hyperplasia (UDH) is one of the most common diagnostic challenges in breast pathology. While proliferations on the ends of this diagnostic spectrum (high-grade DCIS and classic usual ductal hyperplasia) are usually more straightforward to classify, the distinction between low-grade DCIS and ADH can be particularly problematic. An understanding of the biology of these lesions reveals more about their complexity and which lesions are more closely related to each other. When evaluating intraductal proliferations on core needle biopsy samples, pathologists should understand the critical aspects of establishing these diagnoses as well as their clinical impact. This chapter will review practical approaches to the diagnosis of intraductal proliferative lesions on core biopsy as well as some of their diagnostic challenges and clinical implications.]

Published: Sep 17, 2016

Keywords: Intraductal proliferations; Atypical ductal hyperplasia; ADH; Ductal carcinoma in situ; DCIS; Usual ductal hyperplasia; UDH; Diagnostic agreement

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