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A Comprehensive Guide to Core Needle Biopsies of the Breast Fibroepithelial Lesions

A Comprehensive Guide to Core Needle Biopsies of the Breast : Fibroepithelial Lesions [Fibroepithelial lesions of the breast comprise a heterogeneous group characterized by biphasic proliferations of stromal and epithelial components with widely variable clinical behavior, ranging from harmless and benign to frankly malignant. The most prevalent fibroepithelial lesion is the benign fibroadenoma and its variants, and these are commonly encountered on both core needle biopsy and excision specimens. Phyllodes tumors comprise a histologic and biologic spectrum of neoplasms ranging from benign to malignant with potential for recurrence and metastasis, and are far less common than fibroadenomas. Rare periductal stromal tumors, although likely monophasic stromal proliferations, are also included in this group, and many authors consider these lesions to be phyllodes variants. Lastly, mammary hamartomas are benign epithelial-stromal proliferations that may present clinically or radiologically as mass lesions and are included in this category by the World Health Organization (WHO) panel on classification of breast tumors [WHO Classification of Tumours of the Breast. 4th ed. Lyon: International Agency for Research on Cancer (IARC); 2012].] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Comprehensive Guide to Core Needle Biopsies of the Breast Fibroepithelial Lesions

Editors: Shin, Sandra J.
Krings, Gregor; Chen, Yunn-Yi
Springer Journals — Sep 17, 2016
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78 pages

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Publisher
Springer International Publishing
Copyright
© Springer International Publishing Switzerland 2016
ISBN
978-3-319-26289-5
Pages
241 –319
DOI
10.1007/978-3-319-26291-8_7
Publisher site
See Chapter on Publisher Site

Abstract

[Fibroepithelial lesions of the breast comprise a heterogeneous group characterized by biphasic proliferations of stromal and epithelial components with widely variable clinical behavior, ranging from harmless and benign to frankly malignant. The most prevalent fibroepithelial lesion is the benign fibroadenoma and its variants, and these are commonly encountered on both core needle biopsy and excision specimens. Phyllodes tumors comprise a histologic and biologic spectrum of neoplasms ranging from benign to malignant with potential for recurrence and metastasis, and are far less common than fibroadenomas. Rare periductal stromal tumors, although likely monophasic stromal proliferations, are also included in this group, and many authors consider these lesions to be phyllodes variants. Lastly, mammary hamartomas are benign epithelial-stromal proliferations that may present clinically or radiologically as mass lesions and are included in this category by the World Health Organization (WHO) panel on classification of breast tumors [WHO Classification of Tumours of the Breast. 4th ed. Lyon: International Agency for Research on Cancer (IARC); 2012].]

Published: Sep 17, 2016

Keywords: Fibroepithelial; Fibroadenoma; Phyllodes tumor; Periductal stromal tumor; Hamartoma

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