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Am J Cardiovasc Drugs (2018) 18:205–211 https://doi.org/10.1007/s40256-017-0256-x ORIGINAL RESEARCH ARTICLE A Database Cohort Study to Assess the Risk of Angioedema Among Patients with Heart Failure Initiating Angiotensin- Converting Enzyme Inhibitors in the USA 1 2 1 1 1 • • • • • Thy P. Do Arpamas Seetasith Rossella Belleli Raymond G. Schlienger Stefano Corda 2 1 1 • • Chakkarin Burudpakdee Hendrik J. Streefkerk Sigrid Behr Published online: 24 November 2017 Springer International Publishing AG, part of Springer Nature 2017 Abstract 205 days). The 1-year incidence of angioedema per 1000 Introduction Real-world evidence on the risk of angioe- patient-years was 3.3 [95% confidence interval (CI) dema associated with angiotensin-converting enzyme 2.4–4.5]. The incidence was higher in Black [6.2 (95% CI inhibitors (ACEIs) in patients with heart failure (HF) is 3.1–12.5)] than in non-black [2.9 (95% CI 2.1–4.1)] scarce. patients, higher in women [5.2 (95% CI 3.4–7.9)] than in Objective This non-interventional study aimed to estimate men [2.3 (95% CI 1.5–3.6)], and greatest in the first the incidence of and risk factors for angioedema in patients 30 days of ACEI therapy. with HF initiating an ACEI in real-world practice. Conclusions The risk of angioedema in patients with HF Methods
American Journal of Cardiovascular Drugs – Springer Journals
Published: Nov 24, 2017
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