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A Database Cohort Study to Assess the Risk of Angioedema Among Patients with Heart Failure Initiating Angiotensin-Converting Enzyme Inhibitors in the USA

A Database Cohort Study to Assess the Risk of Angioedema Among Patients with Heart Failure... Am J Cardiovasc Drugs (2018) 18:205–211 https://doi.org/10.1007/s40256-017-0256-x ORIGINAL RESEARCH ARTICLE A Database Cohort Study to Assess the Risk of Angioedema Among Patients with Heart Failure Initiating Angiotensin- Converting Enzyme Inhibitors in the USA 1 2 1 1 1 • • • • • Thy P. Do Arpamas Seetasith Rossella Belleli Raymond G. Schlienger Stefano Corda 2 1 1 • • Chakkarin Burudpakdee Hendrik J. Streefkerk Sigrid Behr Published online: 24 November 2017 Springer International Publishing AG, part of Springer Nature 2017 Abstract 205 days). The 1-year incidence of angioedema per 1000 Introduction Real-world evidence on the risk of angioe- patient-years was 3.3 [95% confidence interval (CI) dema associated with angiotensin-converting enzyme 2.4–4.5]. The incidence was higher in Black [6.2 (95% CI inhibitors (ACEIs) in patients with heart failure (HF) is 3.1–12.5)] than in non-black [2.9 (95% CI 2.1–4.1)] scarce. patients, higher in women [5.2 (95% CI 3.4–7.9)] than in Objective This non-interventional study aimed to estimate men [2.3 (95% CI 1.5–3.6)], and greatest in the first the incidence of and risk factors for angioedema in patients 30 days of ACEI therapy. with HF initiating an ACEI in real-world practice. Conclusions The risk of angioedema in patients with HF Methods http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Cardiovascular Drugs Springer Journals

A Database Cohort Study to Assess the Risk of Angioedema Among Patients with Heart Failure Initiating Angiotensin-Converting Enzyme Inhibitors in the USA

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Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Cardiology; Pharmacotherapy; Pharmacology/Toxicology
ISSN
1175-3277
eISSN
1179-187X
DOI
10.1007/s40256-017-0256-x
pmid
29177815
Publisher site
See Article on Publisher Site

Abstract

Am J Cardiovasc Drugs (2018) 18:205–211 https://doi.org/10.1007/s40256-017-0256-x ORIGINAL RESEARCH ARTICLE A Database Cohort Study to Assess the Risk of Angioedema Among Patients with Heart Failure Initiating Angiotensin- Converting Enzyme Inhibitors in the USA 1 2 1 1 1 • • • • • Thy P. Do Arpamas Seetasith Rossella Belleli Raymond G. Schlienger Stefano Corda 2 1 1 • • Chakkarin Burudpakdee Hendrik J. Streefkerk Sigrid Behr Published online: 24 November 2017 Springer International Publishing AG, part of Springer Nature 2017 Abstract 205 days). The 1-year incidence of angioedema per 1000 Introduction Real-world evidence on the risk of angioe- patient-years was 3.3 [95% confidence interval (CI) dema associated with angiotensin-converting enzyme 2.4–4.5]. The incidence was higher in Black [6.2 (95% CI inhibitors (ACEIs) in patients with heart failure (HF) is 3.1–12.5)] than in non-black [2.9 (95% CI 2.1–4.1)] scarce. patients, higher in women [5.2 (95% CI 3.4–7.9)] than in Objective This non-interventional study aimed to estimate men [2.3 (95% CI 1.5–3.6)], and greatest in the first the incidence of and risk factors for angioedema in patients 30 days of ACEI therapy. with HF initiating an ACEI in real-world practice. Conclusions The risk of angioedema in patients with HF Methods

Journal

American Journal of Cardiovascular DrugsSpringer Journals

Published: Nov 24, 2017

References