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A Neuropsychological Analysis of Herpes Simplex Virus-1 (HSV-1) Infection and HSV-1 Encephalitis: Biological Mechanisms, Clinical Presentations, and Brain-Body-Behavior Manifestations

A Neuropsychological Analysis of Herpes Simplex Virus-1 (HSV-1) Infection and HSV-1 Encephalitis:... Virally induced encephalitis, specifically by the herpes simplex-1 virus (HSV-1), is by far the most common cause of encephalitis, or the inflammation of the brain tissue as a result of infection (J NEUROIMMUNOL 295–296:130–138, 2016). This review combines some of the most recent literature regarding the biological mechanisms of HSV-1 to detail its transition to a viral infection of the brain in the form of herpes simplex encephalitis (HSE). Although rare, HSE is a devastating infection with a high mortality rate and few treatment options available that guarantee a successful recovery (J NEUROVIROL 4:346–350, 2013). Accompanied by a range of neurological and psychological symptoms, patients that survive infection with HSE, with the help of proper antiviral medication administration, can experience lifelong impairments to their cognitive functioning and changes to their behavior and personality (NEUROPSYCHOL REHABIL 4–5:450–477, 2007). By documenting the progression of HSV-1 infection to HSE, highlighting some of the clinical presentations described in the literature, and presenting the long-term effects of this infection, this review will emphasize the importance of education as a tool for lowering HSE-related fatalities while suggesting increased research in neurotropic viruses and viral replication in general. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Activitas Nervosa Superior Springer Journals

A Neuropsychological Analysis of Herpes Simplex Virus-1 (HSV-1) Infection and HSV-1 Encephalitis: Biological Mechanisms, Clinical Presentations, and Brain-Body-Behavior Manifestations

Weiland, Mackenzie
Activitas Nervosa Superior , Volume 60 (2) – May 23, 2018
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8 pages

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Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Psychology; Cognitive Psychology; Neuropsychology; Psychology Research; Psychology, general; Experimental Psychology
ISSN
1802-9698
eISSN
1802-9698
DOI
10.1007/s41470-018-0019-2
Publisher site
See Article on Publisher Site

Abstract

Virally induced encephalitis, specifically by the herpes simplex-1 virus (HSV-1), is by far the most common cause of encephalitis, or the inflammation of the brain tissue as a result of infection (J NEUROIMMUNOL 295–296:130–138, 2016). This review combines some of the most recent literature regarding the biological mechanisms of HSV-1 to detail its transition to a viral infection of the brain in the form of herpes simplex encephalitis (HSE). Although rare, HSE is a devastating infection with a high mortality rate and few treatment options available that guarantee a successful recovery (J NEUROVIROL 4:346–350, 2013). Accompanied by a range of neurological and psychological symptoms, patients that survive infection with HSE, with the help of proper antiviral medication administration, can experience lifelong impairments to their cognitive functioning and changes to their behavior and personality (NEUROPSYCHOL REHABIL 4–5:450–477, 2007). By documenting the progression of HSV-1 infection to HSE, highlighting some of the clinical presentations described in the literature, and presenting the long-term effects of this infection, this review will emphasize the importance of education as a tool for lowering HSE-related fatalities while suggesting increased research in neurotropic viruses and viral replication in general.

Journal

Activitas Nervosa Superior – Springer Journals

Published: May 23, 2018

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