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A new case of HTLV1 with rapidly progressive longitudinally extensive transverse myelitis: the importance of early diagnosis in therapeutic response

A new case of HTLV1 with rapidly progressive longitudinally extensive transverse myelitis: the... Acta Neurologica Belgica https://doi.org/10.1007/s13760-023-02289-9 NEURO-IM AGES A new case of HTLV1 with rapidly progressive longitudinally extensive transverse myelitis: the importance of early diagnosis in therapeutic response 1 2 3 2 Celia Romero del Rincón  · Javier B. Pérez  · Antonio Barbosa del Olmo  · Azucena Bautista Hernandez  · 1 1 Carmen Sánchez‑Rodriguez  · Sonia Quintas Received: 3 February 2023 / Accepted: 15 May 2023 © The Author(s) under exclusive licence to Belgian Neurological Society 2023 Keywords HTLV1 · Myelopathy · Paraparesis · Treatment · Glucocorticoid The patient was a 54-year-old Peruvian woman, with no (3/5) and of the sensory impairment. HLTV-1 antibodies previous remarkable medical history. She consulted for were positive in serum, and so were the viral load in both symptoms that began 4 months earlier with right lower limb blood and cerebrospinal fluid. The diagnosis was not better weakness, progressive numbness in both lower limbs and accounted for by another disorder after a complete work-up difficulty in initiating urination. of the patient, including microbiological and immunologi- The physical examination revealed severe 1–2/5 parapa- cal exams. resis, predominantly in the proximal flexors. Muscle reflexes Human T-cell lymphotropic virus 1 (HTLV1) myelopathy were 4/4 with bilateral Achilles tendon clonus and extensor is a classic cause of paraparesis, rare in non-endemic areas plantar response. Tactile hypoaesthesia up to the knees and but http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Neurologica Belgica Springer Journals

A new case of HTLV1 with rapidly progressive longitudinally extensive transverse myelitis: the importance of early diagnosis in therapeutic response

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References (4)

Publisher
Springer Journals
Copyright
Copyright © The Author(s) under exclusive licence to Belgian Neurological Society 2023
ISSN
0300-9009
eISSN
2240-2993
DOI
10.1007/s13760-023-02289-9
Publisher site
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Abstract

Acta Neurologica Belgica https://doi.org/10.1007/s13760-023-02289-9 NEURO-IM AGES A new case of HTLV1 with rapidly progressive longitudinally extensive transverse myelitis: the importance of early diagnosis in therapeutic response 1 2 3 2 Celia Romero del Rincón  · Javier B. Pérez  · Antonio Barbosa del Olmo  · Azucena Bautista Hernandez  · 1 1 Carmen Sánchez‑Rodriguez  · Sonia Quintas Received: 3 February 2023 / Accepted: 15 May 2023 © The Author(s) under exclusive licence to Belgian Neurological Society 2023 Keywords HTLV1 · Myelopathy · Paraparesis · Treatment · Glucocorticoid The patient was a 54-year-old Peruvian woman, with no (3/5) and of the sensory impairment. HLTV-1 antibodies previous remarkable medical history. She consulted for were positive in serum, and so were the viral load in both symptoms that began 4 months earlier with right lower limb blood and cerebrospinal fluid. The diagnosis was not better weakness, progressive numbness in both lower limbs and accounted for by another disorder after a complete work-up difficulty in initiating urination. of the patient, including microbiological and immunologi- The physical examination revealed severe 1–2/5 parapa- cal exams. resis, predominantly in the proximal flexors. Muscle reflexes Human T-cell lymphotropic virus 1 (HTLV1) myelopathy were 4/4 with bilateral Achilles tendon clonus and extensor is a classic cause of paraparesis, rare in non-endemic areas plantar response. Tactile hypoaesthesia up to the knees and but

Journal

Acta Neurologica Belgica – Springer Journals

Published: May 26, 2023

Keywords: HTLV1; Myelopathy; Paraparesis; Treatment; Glucocorticoid

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