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A Practical Guide to Skin CancerMelanoma

A Practical Guide to Skin Cancer: Melanoma [Melanoma most commonly presents as a new or changing pigmented lesion on sun exposed skin. The skin cancer can be categorized into varying subtypes based on its clinical appearance and anatomical location. The prognosis is similar amongst the subtypes with tumor thickness as the most important factor for survival. Melanoma staging depends upon the patient’s symptoms, clinical exam and clinician’s index of suspicion. Surgery is the first line treatment for localized melanoma. Advances in tumor genetics and immunology have led to the development of targeted therapies for metastatic disease.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Practical Guide to Skin CancerMelanoma

Editors: Hanlon, Allison
Divine, Jennifer; Clayton, Anna S.
Springer Journals — May 15, 2018
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24 pages

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Publisher
Springer International Publishing
Copyright
© Springer International Publishing AG, part of Springer Nature 2018
ISBN
978-3-319-74901-3
Pages
117 –141
DOI
10.1007/978-3-319-74903-7_6
Publisher site
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Abstract

[Melanoma most commonly presents as a new or changing pigmented lesion on sun exposed skin. The skin cancer can be categorized into varying subtypes based on its clinical appearance and anatomical location. The prognosis is similar amongst the subtypes with tumor thickness as the most important factor for survival. Melanoma staging depends upon the patient’s symptoms, clinical exam and clinician’s index of suspicion. Surgery is the first line treatment for localized melanoma. Advances in tumor genetics and immunology have led to the development of targeted therapies for metastatic disease.]

Published: May 15, 2018

Keywords: Invasive; Melanoma; Nevi; Genetic mutations; BRAF; MAPK; MEK; NRAS; Kit CDKN2A; Risk factors; UV radiation; Dysplastic nevi; ABCD; Dermoscopy; Melanoma in situ; Nodular melanoma; Metastatic melanoma; Histology; Immunohistochemistry; Breslow depth; Staging; TNM; Prognosis; Survival; Sentinel lymph node; Wide local excision; Margins; Radiation therapy; Chemotherapy; Adjuvant therapy; Immunotherapy; Cytokines; Cancer vaccine; Oncolytic viral therapy; Targeted therapy

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