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A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual DisabilitiesIntroduction

A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with... [We developed these guidelines using drug prescribing information and reviewing the available literature on relevant neuropsychiatric disorders in populations without intellectual disabilities because of the dearth of available ­literature on the population with intellectual disabilities. The idea of combining antiepileptics and mood stabilizers makes sense because there is obvious overlap between what the neurological literature calls antiepileptics and the psychiatric ­literature calls mood stabilizers. Therefore, a total of 21 oral compounds, which are antiepileptics and/or mood stabilizers, were reviewed. In alphabetical order, they are carbamazepine, clonazepam, diazepam, ethosuximide, felbamate, ­gabapentin, lacosamide, lamotrigine, levetiracetam, lithium, lorazepam, oxcarbazepine, phenobarbital, phenytoin, pregabalin, primidone, rufinamide, tiagabine, topiramate, valproate, and zonisamide. In this introduction, we briefly review three concepts, evidence-based medicine, personalized medicine, and drug utilization reviews, in reference to how they have been utilized in these guidelines. The process used in developing these guidelines is then reviewed.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual DisabilitiesIntroduction

Editors: de Leon, Jose
de Leon, Jose
Springer Journals — Feb 1, 2012
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17 pages

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Publisher
Springer US
Copyright
© Springer Science+Business Media, LLC 2012
ISBN
978-1-4614-2011-8
Pages
1 –17
DOI
10.1007/978-1-4614-2012-5_1
Publisher site
See Chapter on Publisher Site

Abstract

[We developed these guidelines using drug prescribing information and reviewing the available literature on relevant neuropsychiatric disorders in populations without intellectual disabilities because of the dearth of available ­literature on the population with intellectual disabilities. The idea of combining antiepileptics and mood stabilizers makes sense because there is obvious overlap between what the neurological literature calls antiepileptics and the psychiatric ­literature calls mood stabilizers. Therefore, a total of 21 oral compounds, which are antiepileptics and/or mood stabilizers, were reviewed. In alphabetical order, they are carbamazepine, clonazepam, diazepam, ethosuximide, felbamate, ­gabapentin, lacosamide, lamotrigine, levetiracetam, lithium, lorazepam, oxcarbazepine, phenobarbital, phenytoin, pregabalin, primidone, rufinamide, tiagabine, topiramate, valproate, and zonisamide. In this introduction, we briefly review three concepts, evidence-based medicine, personalized medicine, and drug utilization reviews, in reference to how they have been utilized in these guidelines. The process used in developing these guidelines is then reviewed.]

Published: Feb 1, 2012

Keywords: Intellectual Disability; Personalized Medicine; Vagus Nerve Stimulation; Adult Individual; Mood Stabilizer

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