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[Morphea (localized scleroderma) is an autoimmune disease characterized by sclerosis of the skin and, in some cases, subcutaneous tissue. It occurs in children and adults. It is distinct from systemic sclerosis, but may nevertheless be associated with significant functional and cosmetic impairment. Morphea has several distinct subtypes, including circumscribed, linear, and generalized, all of which can occur in superficial and deep forms. The linear subtype is more common in children, and the circumscribed is more common in adults. Evaluation is aimed at confirming the diagnosis and clinical subtype, assessing the stage of activity, and determining the potential for/or the presence of morbidity. Therapy includes topical, phototherapy, or systemic treatments and is aimed at halting progression, preventing morbidity, and speeding remission.]
Published: Jun 6, 2014
Keywords: Morphea; Localized scleroderma; Linear scleroderma; Hemifacial atrophy; Parry–Romberg syndrome
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