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A Visual Guide to Scleroderma and Approach to TreatmentSkin Manifestations and Musculoskeletal Disease in SSc

A Visual Guide to Scleroderma and Approach to Treatment: Skin Manifestations and Musculoskeletal... [Clinically, systemic sclerosis is dominated by two features: small vessel vasculopathy and organ fibrosis. These two pathological features are responsible for the clinical manifestations of Raynaud’s phenomenon, digital ulcers, renal crisis, pulmonary arterial hypertension, skin thickening, interstitial lung disease, cardiac complications, and other organ involvement. In spite of this commonality, there is a great deal of heterogeneity in disease expression in scleroderma with some individuals having mild involvement and others with severe and progressive disease.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Visual Guide to Scleroderma and Approach to TreatmentSkin Manifestations and Musculoskeletal Disease in SSc

Editors: Mayes, Maureen D.
Pope, Janet; Mayes, Maureen D.
Springer Journals — Jun 6, 2014
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14 pages

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Publisher
Springer New York
Copyright
© Springer Science+Business Media New York 2014
ISBN
978-1-4939-0979-7
Pages
23 –36
DOI
10.1007/978-1-4939-0980-3_3
Publisher site
See Chapter on Publisher Site

Abstract

[Clinically, systemic sclerosis is dominated by two features: small vessel vasculopathy and organ fibrosis. These two pathological features are responsible for the clinical manifestations of Raynaud’s phenomenon, digital ulcers, renal crisis, pulmonary arterial hypertension, skin thickening, interstitial lung disease, cardiac complications, and other organ involvement. In spite of this commonality, there is a great deal of heterogeneity in disease expression in scleroderma with some individuals having mild involvement and others with severe and progressive disease.]

Published: Jun 6, 2014

Keywords: Raynaud’s phenomenon; Telangiectasias; Pigment changes; Modified Rodnan skin score; Tendon friction rubs; Tenosynovitis

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