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Arch Osteoporos (2006) 1:59–68 DOI 10.1007/s11657-006-0009-y ORIGINAL ARTICLE Age-related changes of bone strength phenotypes: observational follow-up study of hand bone mineral density I. Malkin & G. Bigman & R. Matias & L. Kalichman & M. J. Seibel & E. Kobyliansky & G. Livshits Received: 29 May 2006 /Accepted: 11 September 2006 / Published online: 23 November 2006 International Osteoporosis Foundation and National Osteoporosis Foundation 2006 Abstract age-related changes of hand BMD had higher prediction 2 2 Summary In a cross-sectional and follow-up study, we values in females than in males (R =0.48–0.58 vs R = evaluated age-related changes of hand bone mineral density 0.20–0.29, correspondingly). The compact BMD is more in both sexes using data obtained by digital radiographic sensitive to age changes than the total BMD in both sexes. densitometry in a large Chuvashian cohort. Longitudinal study: Hand BMD loss was higher in males Objectives The aim of the study was to evaluate age-related than in females aged 30–59, but afterwards this trend changes of hand bone mineral density (BMD) in both sexes reversed. The highest loss in both sexes was in ages 50–59. using data obtained by digital radiographic densitometry in a large Chuvashian cohort. Keywords Bone
Archives of Osteoporosis – Springer Journals
Published: Nov 23, 2006
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