Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Augmentation Strategies for Inadequate Antidepressant Response: A Review of Placebo-Controlled Studies

Augmentation Strategies for Inadequate Antidepressant Response: A Review of Placebo-Controlled... Uncontrolled trials of strategies directed at inadequate antidepressant response are prone to falsely positive results. Most of those studies which have used placebo control have assessed augmentation and the addition of lithium to tricyclic antidepressants or serotonin reuptake inhibitors has so far received the most support. A smaller literature shows promise for augmentation with triiodothyronine, pindolol and dehydroepiandrosterone. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Clinical Psychiatry Springer Journals

Augmentation Strategies for Inadequate Antidepressant Response: A Review of Placebo-Controlled Studies

Coryell, William
Annals of Clinical Psychiatry , Volume 12 (3) – Oct 8, 2004
Download PDF
6 pages

Loading next page...
 
/lp/springer-journals/augmentation-strategies-for-inadequate-antidepressant-response-a-owgm1kkgmm
Publisher
Springer Journals
Copyright
Copyright © 2000 by American Academy of Clinical Psychiatrists
Subject
Medicine & Public Health; Neurology; Psychiatry; Psychopharmacology
ISSN
1040-1237
eISSN
1573-3238
DOI
10.1023/A:1009012917837
Publisher site
See Article on Publisher Site

Abstract

Uncontrolled trials of strategies directed at inadequate antidepressant response are prone to falsely positive results. Most of those studies which have used placebo control have assessed augmentation and the addition of lithium to tricyclic antidepressants or serotonin reuptake inhibitors has so far received the most support. A smaller literature shows promise for augmentation with triiodothyronine, pindolol and dehydroepiandrosterone.

Journal

Annals of Clinical Psychiatry – Springer Journals

Published: Oct 8, 2004

References

  • Characteristics and significance of untreated major depressive disorder
    Coryell, W; Endicott, J; Winokur, G
  • Nefazodone and imipramine in major depression: A placebo-controlled trial
    Rickels, K; Schweizer, E; Clary, C; Fox, I; Weise, C
  • Predictors of placebo response in depression
    Brown, WA
  • Clinical features of depressed patients who do and do not improve with placebo
    Brown, WA; Johnson, MF; Chen, MG
  • Which Depressions Respond to Placebo
    Fairchild, CJ; Rush, AJ; Vasavada, N; Giles, DE; Khatami, M
  • Chronicity of depressive episode in relation to antidepressant/placebo response
    Kahn, A; Dager, SR; Cohen, S; Avery, DH; Scherzo, B; Dunner, DL
  • What constitutes an adequate antidepressant trial for fluoxetine
    Schweizer, E; Rickels, K; Amsterdam, JD; Fox, I; Puzzuoli, G; Weise, C
  • Use of pattern analysis to predict differential relapse of remitted patients with major depression during one year of treatment with fluoxetine or placebo
    Stewart, JW; Quitkin, FM; McGrath, PJ
  • Lithium carbonate augmentation of antidepressant treatment
    Heninger, GR; Charney, DS; Sternberg, DE
  • Treatment of endogenous depressions resistant to antidepressants or related drugs by a lithium addiction. Results of a placebocontrolled double-blind study
    Schopf, J; Baumann, P; Lemarchand, T; Ray, M
  • Lithium augmentation therapy in tricyclic-resistant depression
    Stein, G; Burnadt, M
  • A placebocontrolled comparison of lithium and triiodothyronine augmentation of tricyclic antidepressants in unipolar refractory depression
    Joffe, RT; Singer, W; Levitt, AJ; MacDonald, C
  • Placebocontrolled trial of lithium augmentation of fluoxetine and lofepramine
    Katona, CLE; Abou-Salah, MT; Harrison, DA
  • A double-blind, placebo-controlled study of citalopram with and without lithium in the treatment of therapy-resistant depressive patients: A clinical, pharmacokinetic, and pharmacogenetic investigation
    Baumann, P; Souche, A; Montaldi, S
  • Adjunct low dose lithium carbonate in treatment resistant depression: a placebo-controlled study
    Zusky, P; Biederman, J; Rosenbaum, J
  • A rating scale for depression
    Hamilton, M
  • Maintenance of antidepressant effect of sleep deprivation with the help of lithium
    Grube, F; Hartwich, P
  • Ongoing lithium treatment prevents relapse after total sleep deprivation
    Benedetti, F; Colombo, C; Barbini, B; Campori, E; Smeraldi, E
  • Failure of T3 to potentiate tricyclic antidepressant response
    Gitlin, M; Weiner, H; Fairbanks, L; Hershman, J; Friedfeld, N
  • Treatment of imipramineresistant recurrent depression: I. An open clinical trial of adjunctive L-triiodothyronine
    Thase, ME; Kupfer, JD; Jarrett, DB
  • A comparison of triiodothyronine and thyroxin in the potentiation of tricyclic antidepressants
    Joffe, RT; Singer, W
  • Effects of thyroxine as compared with thyroxine plus triiodothyronine in patients with hypothyroidism
    Bunevicius, R; Cazanavicius, G; Zalinkevicius, R; Prange, AJ
  • Efficacy of treatment with trazodone in combination with pindolol or fluoxetine in major depression
    Maes, M; Vandoolaghe, E; Desnyder, R
  • A double-blind randomized, placebo-controlled trial of pindolol augmentation in depressive patients resistant to serotonin reuptake inhibitors
    Perez, V; Soler, J; Puigdemont, D; Alvarez, E; Afectius, G; Artigas, F
  • Randomized, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment
    Perez, V.; Gilaberte, I; Faries, D; Alvarez, E; Artigas, F
  • Paroxetine and pindolol: A randomized trial of serotonergic autoreceptor blockade in the reduction of antidepressant latency
    Tome, MB; Isaac, MT; Harte, R; Holland, C
  • How long should pindolol be associated with paroxetine to improve the antidepressant response
    Zanardi, R; Artigas, F; Franchini, L
  • Effect of pindolol on onset of action of paroxetine in the treatment of major depression: Intermediate analysis of a double-blind, placebo-controlled Trial
    Bordet, R; Thomas, P; Dupuis, B
  • Faster onset of action of fluvoxamine in combination with pindolol in the treatment of delusional depression: A controlled study
    Zanardi, R; Franchini, L; Gasperini, M; Lucca, A; Smeraldi, E; Perez, J
  • The use of pindolol with fluoxetine in the treatment of major depression: Final results from a double-blind, placebo-controlled trial
    Berman, RM; Anand, A; Cappiello, A
  • Sustained antidepressant effect of sleep deprivation combined with pindolol in bipolar depression
    Smeraldi, E; Benedetti, F; Barbini, B; Campori, E; Colombo, C
  • A meta-analysis of the effect of hormone replacement therapy upon depressed mood
    Zweifel, JE; O'Brien, WH
  • Estrogen therapy for severe persistent depressions in women
    Klaiber, EL; Broverman, DM; Vogel, W; Kobayashi, T
  • Lack of efficacy of estrogen supplementation to imipramine in resistant female depressives
    Shapira, B; Oppenheim, G; Zohar, J; Segal, M; Malach, D; Belmaker, RM
  • Double-blind treatment of major depression with the dehydroepiandrosterone
    Wolkowitz, OM; Reus, DIAGNOSIS; Keebler, A; Nelson, N; Friedland, M; Brizendine, L; Roberts, E
  • Dehydroepiandrosterone treatment of mid-life dysthymia
    Bloch, M; Schmidt, PJ; Danaceau, MA; Adams, LF; Rubinow, DR