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Basic Serological TestingRheumatoid Factor (RF)

Basic Serological Testing: Rheumatoid Factor (RF) [Rheumatoid arthritis is a chronic autoimmune disease associated with autoantibodies known as rheumatoid factor (RF). RF is produced by autoreactive B cells against self-IgG Fc regions. Therefore, RF is wieldy used in clinical laboratories as a biomarker for rheumatoid arthritis. This chapter describes the principle, applications, reagents, steps, results interpretation, and the limitations of the most commonly used test to detect RF.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

Basic Serological TestingRheumatoid Factor (RF)

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Publisher
Springer International Publishing
Copyright
© Springer International Publishing AG, part of Springer Nature 2018
ISBN
978-3-319-77693-4
Pages
49 –53
DOI
10.1007/978-3-319-77694-1_7
Publisher site
See Chapter on Publisher Site

Abstract

[Rheumatoid arthritis is a chronic autoimmune disease associated with autoantibodies known as rheumatoid factor (RF). RF is produced by autoreactive B cells against self-IgG Fc regions. Therefore, RF is wieldy used in clinical laboratories as a biomarker for rheumatoid arthritis. This chapter describes the principle, applications, reagents, steps, results interpretation, and the limitations of the most commonly used test to detect RF.]

Published: May 24, 2018

Keywords: Autoimmune; RA; RF; ACPA; Latex agglutination; Gamma globulin

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