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Bipolar II Depression with Melancholic Features

Bipolar II Depression with Melancholic Features Bipolar II depression with melancholic features has been understudied. The aims of the present study were to find the prevalence of melancholic features in bipolar II depression and in unipolar depression, and to compare melancholic with nonmelancholic bipolar II/ unipolar depression in private practice. One hundred and sixty two consecutive unipolar and bipolar II depressed outpatients were interviewed with the DSM-IV Structured Clinical Interview, the Montgomery–Asberg Depression Rating Scale, and the Global Assessment of Functioning Scale. Melancholic features were present in 19.2% of bipolar II patients and in 22.6% of unipolar patients, a nonsignificant difference. Melancholic bipolar II patients versus nonmelancholic bipolar II patients had significantly more psychosis and higher severity. All the other variables (age, age at onset, gender, illness duration, recurrences, atypical features, chronicity, comorbidity) were not significantly different. Melancholic bipolar II patients versus melancholic unipolar patients were not significantly different. Nonmelancholic bipolar II patients versus nonmelancholic unipolar patients had significantly lower age, lower age at onset, more atypical features, and more comorbidity. The prevalence of melancholic features in bipolar II depression in private practice was higher than previously reported in academic centers. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Clinical Psychiatry Springer Journals

Bipolar II Depression with Melancholic Features

Benazzi, Franco
Annals of Clinical Psychiatry , Volume 12 (1) – Sep 30, 2004
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Publisher
Springer Journals
Copyright
Copyright © 2000 by American Academy of Clinical Psychiatrists
Subject
Medicine & Public Health; Neurology; Psychiatry; Psychopharmacology
ISSN
1040-1237
eISSN
1573-3238
DOI
10.1023/A:1009022910082
Publisher site
See Article on Publisher Site

Abstract

Bipolar II depression with melancholic features has been understudied. The aims of the present study were to find the prevalence of melancholic features in bipolar II depression and in unipolar depression, and to compare melancholic with nonmelancholic bipolar II/ unipolar depression in private practice. One hundred and sixty two consecutive unipolar and bipolar II depressed outpatients were interviewed with the DSM-IV Structured Clinical Interview, the Montgomery–Asberg Depression Rating Scale, and the Global Assessment of Functioning Scale. Melancholic features were present in 19.2% of bipolar II patients and in 22.6% of unipolar patients, a nonsignificant difference. Melancholic bipolar II patients versus nonmelancholic bipolar II patients had significantly more psychosis and higher severity. All the other variables (age, age at onset, gender, illness duration, recurrences, atypical features, chronicity, comorbidity) were not significantly different. Melancholic bipolar II patients versus melancholic unipolar patients were not significantly different. Nonmelancholic bipolar II patients versus nonmelancholic unipolar patients had significantly lower age, lower age at onset, more atypical features, and more comorbidity. The prevalence of melancholic features in bipolar II depression in private practice was higher than previously reported in academic centers.

Journal

Annals of Clinical Psychiatry – Springer Journals

Published: Sep 30, 2004

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