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Acta Neurologica Belgica https://doi.org/10.1007/s13760-023-02256-4 LE T TER TO THE EDITOR Chronic inflammatory axonal polyneuropathy with myositis: a rare presentation 1 1 1 2 B. Ragavendar · Ramkumar Sugumaran · Sunil K. Narayan · B. H. Srinivas Received: 20 January 2023 / Accepted: 25 March 2023 © The Author(s) under exclusive licence to Belgian Neurological Society 2023 We describe two cases of CIAP with response to Immu- in fibre size and shape without any significant Perifascicular nomodulation therapy and we also demonstrate the rare or Perivascular atrophy. Immunohistochemistry could not be association of inflammatory polyneuropathy with myositis, done due to logistical issues. We administered intravenous referred to as “Neuromyositis”, as evidenced by Muscle immunoglobulin (IVIg: 0.4 g/kg/day for 5 days) before start- and nerve biopsy which has not been previously reported ing oral steroids (1 mg/kg/day) and then tapering over the in CIAP [1]. next few months based upon the response. After 1 month, A 32-year-old male, presented with insidious onset the patient was given IV Cyclophosphamide 750 mg/m gradually progressive numbness and weakness of all four for 3 doses every 4 weeks with routine monitoring of liver limbs, lower limbs followed by upper limbs with aching function test (LFT), complete blood count (CBC) and renal muscle pain in the thigh and gluteal
Acta Neurologica Belgica – Springer Journals
Published: Dec 1, 2023
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