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Correlation between antibiotic use and resistance in a hospital: Temporary and ward-specific observations

Correlation between antibiotic use and resistance in a hospital: Temporary and ward-specific... Infection Clinical and Epidemiological Study Correlation Between Antibiotic Use and Resistance in a Hospital: Temporary and Ward-Specific Observations I. Willemsen, D. Bogaers-Hofman, M. Winters, J. Kluytmans Abstract antimicrobial agents [3]. In general, the development of Objectives: The objectives of this study were to determine resistance to microorganisms is associated with the (1) the increase in antimicrobial resistance to frequently used amount of use of antimicrobial agents, as shown repeat- antibiotics in the hospital setting over time and (2) the edly in studies at national and regional levels [4, 5]. The correlation between the amount of use of an antibiotic in a use of antimicrobial agents in the entire hospital corre- specific medical specialty and the observed resistance to that lates with the observed level of resistance [6]. However, antibiotic in that specialty. the relationship between the amount of use within indi- Method: The total use of antibiotics and the use of ciproflox- vidual medical specialties of a hospital and the observed acin (CIP), co-amoxicillin + clavulanic acid (AMCL) and first- level of resistance in this medical specialty has not been and second-generation cephalosporins (CEF), respectively, in clearly established. Harbarth et al. [7] investigated this individual medical specialties were measured http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Infection Springer Journals

Correlation between antibiotic use and resistance in a hospital: Temporary and ward-specific observations

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References (28)

Publisher
Springer Journals
Copyright
Copyright © 2009 by Springer
Subject
Medicine & Public Health; Internal Medicine ; General Practice / Family Medicine; Infectious Diseases
ISSN
0300-8126
eISSN
1439-0973
DOI
10.1007/s15010-009-8325-y
pmid
19499184
Publisher site
See Article on Publisher Site

Abstract

Infection Clinical and Epidemiological Study Correlation Between Antibiotic Use and Resistance in a Hospital: Temporary and Ward-Specific Observations I. Willemsen, D. Bogaers-Hofman, M. Winters, J. Kluytmans Abstract antimicrobial agents [3]. In general, the development of Objectives: The objectives of this study were to determine resistance to microorganisms is associated with the (1) the increase in antimicrobial resistance to frequently used amount of use of antimicrobial agents, as shown repeat- antibiotics in the hospital setting over time and (2) the edly in studies at national and regional levels [4, 5]. The correlation between the amount of use of an antibiotic in a use of antimicrobial agents in the entire hospital corre- specific medical specialty and the observed resistance to that lates with the observed level of resistance [6]. However, antibiotic in that specialty. the relationship between the amount of use within indi- Method: The total use of antibiotics and the use of ciproflox- vidual medical specialties of a hospital and the observed acin (CIP), co-amoxicillin + clavulanic acid (AMCL) and first- level of resistance in this medical specialty has not been and second-generation cephalosporins (CEF), respectively, in clearly established. Harbarth et al. [7] investigated this individual medical specialties were measured

Journal

InfectionSpringer Journals

Published: Jun 4, 2009

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