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review Allergo J Int (2017) 26:122–128 DOI 10.1007/s40629-017-0024-0 Dealing with absolute and relative contraindications to specific immunotherapy using Hymenoptera venoms Andrea Bauer · Franziska Ruëff Received: 19 February 2017 / Accepted: 17 March 2017 / Published online: 4 May 2017 © Springer Medizin Verlag GmbH 2017 Abstract tion of HV-SIT. Some of these contraindications are, by Background Acute infectious disorders, uncontrolled their very nature, temporary. In other cases, therapy bronchial asthma, severe chronic inflammatory dis- can be initiated once the underlying disease has been orders, severe cardiovascular disorders, autoimmune optimally treated. Relative contraindications to the or immunodeficiency disorders, active or progres- initiation of HV-SIT include autoimmune disorders in sive cancer, acquired immunodeficiency syndrome remission, immune defects and immunosuppressive (AIDS), treatment initiation during pregnancy, as well therapy, well-controlled chronic infectious diseases, as medication with β-blockers and angiotensin-con- category A and B HIV, partially controlled bronchial verting enzyme (ACE) inhibitors, among others, are asthma, limited compliance, age below 5 years, can- considered either absolute or relative contraindica- cer in remission, comedication with ACE inhibitors tions to specific immunotherapy using Hymenoptera and β-blockers, as well as treatment (continuation) venom (HV-SIT). Some of the contraindications listed during pregnancy. In the case of relative
Allergo Journal International – Springer Journals
Published: May 4, 2017
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