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The alkali-burned corneas of 12 rabbits were studied with fluorescence microscopy 1 week, 3 weeks, and 6 months after injury to identify the arrangement of catecholaminergic nerve fibers (CNF) and related levels of norepinephrine. In the wounded corneas, CNF were reduced at both 1 and 3 weeks and were restored by 6 months, as shown by histofluorescent staining. Biochemical results showed that norepinephrine also passes through surviving, degenerating, and regenerating phases.
Annals of Ophthalmology – Springer Journals
Published: Apr 26, 2000
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