Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

DNMT3A mutations in acute myeloid leukemia

DNMT3A mutations in acute myeloid leukemia New studies reveal that 20% of individuals with acute myeloid leukemia harbor somatic mutations in DNMT3A (encoding DNA methyltransferase 3A). Although these leukemias have some gene expression and DNA methylation changes, a direct link between mutant DNMT3A, epigenetic changes and pathogenesis remains to be established. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Genetics Springer Journals

DNMT3A mutations in acute myeloid leukemia

Nature Genetics , Volume 43 (4) – Mar 29, 2011

Loading next page...
 
/lp/springer-journals/dnmt3a-mutations-in-acute-myeloid-leukemia-Cmo1OapUUm

References (15)

Publisher
Springer Journals
Copyright
Copyright © 2011 by Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.
Subject
Biomedicine; Biomedicine, general; Human Genetics; Cancer Research; Agriculture; Gene Function; Animal Genetics and Genomics
ISSN
1061-4036
eISSN
1546-1718
DOI
10.1038/ng0411-289
Publisher site
See Article on Publisher Site

Abstract

New studies reveal that 20% of individuals with acute myeloid leukemia harbor somatic mutations in DNMT3A (encoding DNA methyltransferase 3A). Although these leukemias have some gene expression and DNA methylation changes, a direct link between mutant DNMT3A, epigenetic changes and pathogenesis remains to be established.

Journal

Nature GeneticsSpringer Journals

Published: Mar 29, 2011

There are no references for this article.