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Effects of cognitive behavioral therapy for insomnia and armodafinil on quality of life in cancer survivors: a randomized placebo-controlled trial

Effects of cognitive behavioral therapy for insomnia and armodafinil on quality of life in cancer... Purpose Cancer-related insomnia is associated with dimin- CBT-I + placebo, CBT-I + armodafinil, armodafinil, and placebo ished quality of life (QOL), suggesting that improvement in was 9.6 (SE = 1.8; p < 0.0001), 11.6 (SE = 1.8; p < 0.0001), −0.2 insomnia may improve QOL in cancer survivors. Cognitive (SE = 3.2; p = 0.964), and 3.3 (SE = 2.0; p = 0.124), respectively. behavioral therapy for insomnia (CBT-I) has been shown to ANCOVA controlling for pre-intervention scores showed that improve insomnia, but less is known regarding its effect on participants receiving CBT-I had significantly improved QOL at QOL and whether improvement in insomnia corresponds to post-intervention compared to those not receiving CBT-I improved QOL. The present analysis examines the effects of (p < 0.0001, effect size = 0.57), with benefits being maintained CBT-I, with and without armodafinil, on QOL both directly at the 3-month follow-up. Path analysis revealed that this im- and indirectly through improvements of insomnia. provement in QOL was due to improvement in insomnia severity Methods This is an analysis of 95 cancer survivors for a spec- (p = 0.002), and Pearson correlations showed that changes in ified secondary aim of a four-arm randomized controlled trial http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Cancer Survivorship: Research and Practice Springer Journals

Effects of cognitive behavioral therapy for insomnia and armodafinil on quality of life in cancer survivors: a randomized placebo-controlled trial

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References (44)

Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer Science+Business Media New York
Subject
Medicine & Public Health; Public Health; Oncology; Health Promotion and Disease Prevention; Health Informatics; Quality of Life Research; Primary Care Medicine
ISSN
1932-2259
eISSN
1932-2267
DOI
10.1007/s11764-017-0597-0
pmid
28105576
Publisher site
See Article on Publisher Site

Abstract

Purpose Cancer-related insomnia is associated with dimin- CBT-I + placebo, CBT-I + armodafinil, armodafinil, and placebo ished quality of life (QOL), suggesting that improvement in was 9.6 (SE = 1.8; p < 0.0001), 11.6 (SE = 1.8; p < 0.0001), −0.2 insomnia may improve QOL in cancer survivors. Cognitive (SE = 3.2; p = 0.964), and 3.3 (SE = 2.0; p = 0.124), respectively. behavioral therapy for insomnia (CBT-I) has been shown to ANCOVA controlling for pre-intervention scores showed that improve insomnia, but less is known regarding its effect on participants receiving CBT-I had significantly improved QOL at QOL and whether improvement in insomnia corresponds to post-intervention compared to those not receiving CBT-I improved QOL. The present analysis examines the effects of (p < 0.0001, effect size = 0.57), with benefits being maintained CBT-I, with and without armodafinil, on QOL both directly at the 3-month follow-up. Path analysis revealed that this im- and indirectly through improvements of insomnia. provement in QOL was due to improvement in insomnia severity Methods This is an analysis of 95 cancer survivors for a spec- (p = 0.002), and Pearson correlations showed that changes in ified secondary aim of a four-arm randomized controlled trial

Journal

Journal of Cancer Survivorship: Research and Practice – Springer Journals

Published: Jan 19, 2017

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