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Purpose Cancer-related insomnia is associated with dimin- CBT-I + placebo, CBT-I + armodafinil, armodafinil, and placebo ished quality of life (QOL), suggesting that improvement in was 9.6 (SE = 1.8; p < 0.0001), 11.6 (SE = 1.8; p < 0.0001), −0.2 insomnia may improve QOL in cancer survivors. Cognitive (SE = 3.2; p = 0.964), and 3.3 (SE = 2.0; p = 0.124), respectively. behavioral therapy for insomnia (CBT-I) has been shown to ANCOVA controlling for pre-intervention scores showed that improve insomnia, but less is known regarding its effect on participants receiving CBT-I had significantly improved QOL at QOL and whether improvement in insomnia corresponds to post-intervention compared to those not receiving CBT-I improved QOL. The present analysis examines the effects of (p < 0.0001, effect size = 0.57), with benefits being maintained CBT-I, with and without armodafinil, on QOL both directly at the 3-month follow-up. Path analysis revealed that this im- and indirectly through improvements of insomnia. provement in QOL was due to improvement in insomnia severity Methods This is an analysis of 95 cancer survivors for a spec- (p = 0.002), and Pearson correlations showed that changes in ified secondary aim of a four-arm randomized controlled trial
Journal of Cancer Survivorship: Research and Practice – Springer Journals
Published: Jan 19, 2017
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