Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Electrospun Textile Strategies in Tendon to Bone Junction Reconstruction

Electrospun Textile Strategies in Tendon to Bone Junction Reconstruction The repair of tendon to bone junction (TBJ) remains a tremendous challenge in tissue engineering due to the complicated structure, components, mechanical properties, and cell types. In order to reconstruct the tissue and restore its functionality, biomedical scaffolds with hierarchical and gradient structures have been fabricated by various strategies. In recent decades, electrospinning has become one of the most popular methods in fabricating TBJ scaffolds due to easy fabrication, high porosity, and ECM-like nano-scale structure. However, mechanical properties are the pain point of electrospun biomedical scaffolds. Traditional textile technology can be exploited to compensate for this weakness, which will be deeply discussed here. This review will start with a brief introduction to the structure and function of the native TBJ tissue and a short overview of electrospinning technology. Then, different electrospun biomedical scaffolds for TBJ repair will be summarized and compared. Furthermore, some advanced technologies and modification methods in fabricating functionalized electrospun TBJ scaffolds are discussed. In the end, current challenges and solutions are being proposed, which would provide instruction for the research of electrospun textile TBJ scaffolds.Graphical Abstract[graphic not available: see fulltext] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Advanced Fiber Materials Springer Journals

Electrospun Textile Strategies in Tendon to Bone Junction Reconstruction

Download PDF
27 pages

Loading next page...
 
/lp/springer-journals/electrospun-textile-strategies-in-tendon-to-bone-junction-qYqMPXPU9e

References (184)

Publisher
Springer Journals
Copyright
Copyright © Donghua University, Shanghai, China 2022. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
ISSN
2524-7921
eISSN
2524-793X
DOI
10.1007/s42765-022-00233-9
Publisher site
See Article on Publisher Site

Abstract

The repair of tendon to bone junction (TBJ) remains a tremendous challenge in tissue engineering due to the complicated structure, components, mechanical properties, and cell types. In order to reconstruct the tissue and restore its functionality, biomedical scaffolds with hierarchical and gradient structures have been fabricated by various strategies. In recent decades, electrospinning has become one of the most popular methods in fabricating TBJ scaffolds due to easy fabrication, high porosity, and ECM-like nano-scale structure. However, mechanical properties are the pain point of electrospun biomedical scaffolds. Traditional textile technology can be exploited to compensate for this weakness, which will be deeply discussed here. This review will start with a brief introduction to the structure and function of the native TBJ tissue and a short overview of electrospinning technology. Then, different electrospun biomedical scaffolds for TBJ repair will be summarized and compared. Furthermore, some advanced technologies and modification methods in fabricating functionalized electrospun TBJ scaffolds are discussed. In the end, current challenges and solutions are being proposed, which would provide instruction for the research of electrospun textile TBJ scaffolds.Graphical Abstract[graphic not available: see fulltext]

Journal

Advanced Fiber Materials – Springer Journals

Published: Jun 1, 2023

Keywords: Electrospun; Textile; Tendon to bone; Tissue engineering; Biomimetic

There are no references for this article.