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J Cancer Surviv (2017) 11:320–328 DOI 10.1007/s11764-016-0590-z Health-related behaviors and mortality outcomes in women diagnosed with ductal carcinoma in situ 1,2 1,2 2,3 4 Christopher Thomas Veal & Vicki Hart & Susan G. Lakoski & John M. Hampton & 4,5 6,7 2,8,9 Ronald E. Gangnon & Polly A. Newcomb & Stephen T. Higgins & 2,4 1,2,9 Amy Trentham-Dietz & Brian L. Sprague Received: 27 July 2016 /Accepted: 16 December 2016 /Published online: 5 January 2017 Springer Science+Business Media New York 2017 Abstract hazard ratios (HR) and 95% confidence intervals (CI) for Purpose Women diagnosed with ductal carcinoma in situ mortality after DCIS, with adjustment for patient (DCIS) of the breast are at greater risk of dying from cardio- sociodemographic, comorbidity, and treatment factors. vascular disease and other causes than from breast cancer, yet Results Over a mean of 6.7 years of follow-up, 196 deaths associations between health-related behaviors and mortality occurred. All-cause mortality was elevated among women outcomes after DCIS have not been well studied. who were current smokers 1 year prior to diagnosis Methods We examined the association of body mass index, (HR = 2.17 [95% CI 1.48, 3.18] vs. never smokers) and re- physical activity, alcohol consumption,
Journal of Cancer Survivorship: Research and Practice – Springer Journals
Published: Jan 5, 2017
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