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Gary Wang, V. Kurra, J. Gainor, R. Sullivan, K. Flaherty, Susanna Lee, F. Fintelmann (2017)Immune Checkpoint Inhibitor Cancer Therapy: Spectrum of Imaging Findings.
Radiographics : a review publication of the Radiological Society of North America, Inc, 37 7
F. Martins, Latifyan Sofiya, G. Sykiotis, F. Lamine, M. Maillard, M. Fraga, K. Shabafrouz, C. Ribi, A. Cairoli, Y. Guex-Crosier, T. Kuntzer, O. Michielin, S. Peters, G. Coukos, F. Spertini, John Thompson, M. Obeid (2019)Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance
Nature Reviews Clinical Oncology
Y. Zen, M. Yeh (2018)Hepatotoxicity of immune checkpoint inhibitors: a histology study of seven cases in comparison with autoimmune hepatitis and idiosyncratic drug-induced liver injury
Modern Pathology, 31
S. Yoneda, A. Imagawa, Yoshiya Hosokawa, M. Baden, T. Kimura, S. Uno, K. Fukui, Kunihito Goto, M. Uemura, H. Eguchi, H. Iwahashi, J. Kozawa, I. Shimomura (2019)T-Lymphocyte Infiltration to Islets in the Pancreas of a Patient Who Developed Type 1 Diabetes After Administration of Immune Checkpoint Inhibitors
Diabetes Care, 42
R. Thoeni (2012)The revised Atlanta classification of acute pancreatitis: its importance for the radiologist and its effect on treatment.
Radiology, 262 3
M. Baker, R. Nelson, M. Rosen, M. Blake, B. Cash, N. Hindman, I. Kamel, H. Kaur, R. Piorkowski, A. Qayyum, Gail Yarmish (2014)ACR Appropriateness Criteria® acute pancreatitis.
Ultrasound quarterly, 30 4
C. Friedman, V. Clark, A. Raikhel, T. Barz, A. Shoushtari, P. Momtaz, M. Callahan, J. Wolchok, P. Chapman, M. Hellmann, M. Postow (2017)Thinking Critically About Classifying Adverse Events: Incidence of Pancreatitis in Patients Treated With Nivolumab + Ipilimumab.
Journal of the National Cancer Institute, 109 4
Kiran Busireddy, M. AlObaidy, M. Ramalho, J. Kalubowila, B. Liu, I. Santagostino, R. Semelka (2014)Pancreatitis-imaging approach.
World journal of gastrointestinal pathophysiology, 5 3
T. Shimosegawa, S. Chari, L. Frulloni, T. Kamisawa, S. Kawa, M. Mino‐Kenudson, Myung-Hwan Kim, G. Klöppel, M. Lerch, M. Löhr, K. Notohara, K. Okazaki, A. Schneider, Lizhi Zhang (2011)International Consensus Diagnostic Criteria for Autoimmune Pancreatitis: Guidelines of the International Association of Pancreatology
L. Lee, D. Sahani (2014)Autoimmune pancreatitis in the context of IgG4-related disease: review of imaging findings.
World journal of gastroenterology, 20 41
S. Tirumani, N. Ramaiya, A. Keraliya, Nancy Bailey, P. Ott, F. Hodi, M. Nishino (2015)Radiographic Profiling of Immune-Related Adverse Events in Advanced Melanoma Patients Treated with Ipilimumab
Cancer Immunology Research, 3
Z. Hlavatá, C. Solinas, P. Silva, M. Porcu, L. Saba, K. Willard-Gallo, M. Scartozzi (2018)The Abscopal Effect in the Era of Cancer Immunotherapy: a Spontaneous Synergism Boosting Anti-tumor Immunity?
Targeted Oncology, 13
Kamraan Madhani, J. Farrell (2018)Management of Autoimmune Pancreatitis.
Gastrointestinal endoscopy clinics of North America, 28 4
B. Xiao, Xiao-Ming Zhang (2010)Magnetic resonance imaging for acute pancreatitis.
World journal of radiology, 2 8
Angeliki Stamatouli, Z. Quandt, A. Perdigoto, P. Clark, H. Kluger, S. Weiss, S. Gettinger, M. Sznol, A. Young, R. Rushakoff, James Lee, J. Bluestone, Mark Anderson, K. Herold (2018)Collateral Damage: Insulin-Dependent Diabetes Induced With Checkpoint Inhibitors
P. Banks, T. Bollen, C. Dervenis, H. Gooszen, C. Johnson, Michel Sarr, G. Tsiotos, S. Vege (2012)Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus
Bryan Foster, Kyle Jensen, G. Bakis, A. Shaaban, F. Coakley (2016)Revised Atlanta Classification for Acute Pancreatitis: A Pictorial Essay.
Radiographics : a review publication of the Radiological Society of North America, Inc, 36 3
E. Champeaux-Orange, A. Reynaud-Bougnoux, I. Barillot (2010)Évaluation par le patient de la toxicité aiguë de la radiothérapie pelvienne selon la Common Terminology Criteria for Adverse Events, version 3.0 (CTCAE v3.0) : rêve ou réalité ?
Cancer Radiotherapie, 14
Pramod Darvin, S. Toor, V. Nair, E. Elkord (2018)Immune checkpoint inhibitors: recent progress and potential biomarkers
Experimental & Molecular Medicine, 50
Hamzah Abu-Sbeih, Tenglong Tang, Yang Lu, S. Thirumurthi, M. Altan, A. Jazaeri, R. Dadu, E. Coronel, Yinghong Wang (2019)Clinical characteristics and outcomes of immune checkpoint inhibitor-induced pancreatic injury
Journal for Immunotherapy of Cancer, 7
M. Porcu, C. Solinas, P. Garofalo, E. Azambuja, M. Scartozzi, K. Willard-Gallo, M. Preusser, L. Saba (2018)Radiological evaluation of response to immunotherapy in brain tumors: Where are we now and where are we going?
Critical reviews in oncology/hematology, 126
Vivek Kumar, N. Chaudhary, M. Garg, C. Floudas, P. Soni, A. Chandra (2017)Current Diagnosis and Management of Immune Related Adverse Events (irAEs) Induced by Immune Checkpoint Inhibitor Therapy
Frontiers in Pharmacology, 8
Behzad Rowshanravan, Neil Halliday, D. Sansom (2018)CTLA-4: a moving target in immunotherapy.
Blood, 131 1
Nabil Choueiri, N. Balcı, S. Alkaade, F. Burton (2010)Advanced Imaging of Chronic Pancreatitis
Current Gastroenterology Reports, 12
Y. Eshet, E. Baruch, R. Shapira-Frommer, Yael Steinberg-Silman, T. Kuznetsov, Guy Ben-Betzalel, S. Daher, I. Gluck, N. Asher, S. Apter, J. Schachter, J. Bar, B. Boursi, G. Markel (2018)Clinical Significance of Pancreatic Atrophy Induced by Immune-Checkpoint Inhibitors: A Case–Control Study
Cancer Immunology Research, 6
Alyssa Krasinskas, Amit Raina, Asif Khalid, Mitchell Tublin, Dhiraj Yadav (2007)Autoimmune pancreatitis.
Gastroenterology clinics of North America, 36 2
L. Dickerson, A. Farooq, F. Bano, J. Kleeff, C. Halloran, M. Raraty, P. Ghaneh, R. Sutton, P. Whelan, F. Campbell, P. Healey, J. Neoptolemos, V. Yip (2018)Differentiation of Autoimmune Pancreatitis from Pancreatic Cancer Remains Challenging
World Journal of Surgery, 43
T. Bollen (2016)Acute pancreatitis: international classification and nomenclature.
Clinical radiology, 71 2
M. Petrov, S. Shanbhag, M. Chakraborty, A. Phillips, J. Windsor (2010)Organ failure and infection of pancreatic necrosis as determinants of mortality in patients with acute pancreatitis.
Gastroenterology, 139 3
C. Wullstein, W. Bechstein (2004)[Acute pancreatitis].
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 75 6
Jean-Marie Michot, C. Bigenwald, S. Champiat, M. Collins, F. Carbonnel, S. Postel-Vinay, A. Berdelou, A. Varga, R. Bahleda, A. Hollebecque, C. Massard, A. Fuerea, V. Ribrag, A. Gazzah, J. Armand, N. Amellal, E. Angevin, N. Noel, C. Boutros, C. Mateus, C. Robert, J. Soria, A. Marabelle, O. Lambotte (2016)Immune-related adverse events with immune checkpoint blockade: a comprehensive review.
European journal of cancer, 54
C. Solinas, M. Porcu, Z. Hlavatá, P. Silva, M. Puzzoni, K. Willard-Gallo, M. Scartozzi, L. Saba (2017)Critical features and challenges associated with imaging in patients undergoing cancer immunotherapy.
Critical reviews in oncology/hematology, 120
L. Saba, Mainak Biswas, Venkatanareshbabu Kuppili, E. Godia, Harman Suri, D. Edla, Tomaž Omerzu, J. Laird, N. Khanna, S. Mavrogeni, A. Protogerou, P. Sfikakis, V. Viswanathan, G. Kitas, A. Nicolaides, Ajay Gupta, J. Suri (2019)The present and future of deep learning in radiology.
European journal of radiology, 114
J. Naidoo, Xuan Wang, K. Woo, T. Iyriboz, D. Halpenny, J. Cunningham, J. Chaft, N. Segal, M. Callahan, A. Lesokhin, J. Rosenberg, M. Voss, C. Rudin, H. Rizvi, X. Hou, K. Rodriguez, M. Albano, R. Gordon, Charles Leduc, N. Rekhtman, Bianca Harris, A. Menzies, A. Guminski, M. Carlino, B. Kong, J. Wolchok, M. Postow, G. Long, M. Hellmann (2017)Pneumonitis in Patients Treated With Anti-Programmed Death-1/Programmed Death Ligand 1 Therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 35 7
Lizhi Zhang, S. Chari, T. Smyrk, V. Deshpande, G. Klöppel, M. Kojima, Xiuli Liu, D. Longnecker, M. Mino‐Kenudson, K. Notohara, M. Rodríguez-Justo, A. Srivastava, G. Zamboni, Y. Zen (2011)Autoimmune Pancreatitis (AIP) Type 1 and Type 2: An International Consensus Study on Histopathologic Diagnostic Criteria
N. Balcı, S. Alkaade, L. Magas, A. Momtahen, F. Burton (2008)Suspected chronic pancreatitis with normal MRCP: Findings on MRI in correlation with secretin MRCP
Journal of Magnetic Resonance Imaging, 27
C. Solinas, M. Porcu, P. Silva, M. Musi, S. Aspeslagh, M. Scartozzi, K. Willard-Gallo, S. Mariotti, L. Saba (2018)Cancer immunotherapy-associated hypophysitis.
Seminars in oncology, 45 3
M. Porcu, P. Silva, C. Solinas, A. Battaglia, M. Schena, M. Scartozzi, D. Bron, J. Suri, K. Willard-Gallo, D. Sangiolo, L. Saba (2019)Immunotherapy Associated Pulmonary Toxicity: Biology Behind Clinical and Radiological Features
J. Haanen, M. Obeid, L. Spain, F. Carbonnel, Y. Wang, C. Robert, A. Lyon, W. Wick, M. Kostine, S. Peters, K. Jordan, J. Larkin (2022)Management of toxicities from immunotherapy: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Annals of oncology : official journal of the European Society for Medical Oncology
L. Drake, Munazza Anis, C. Lawrence (2012)Accuracy of Magnetic Resonance Cholangiopancreatography in Identifying Pancreatic Duct Disruption
Journal of Clinical Gastroenterology, 46
V. Hagelstein, I. Ortland, A. Wilmer, S. Mitchell, U. Jaehde (2016)Validation of the German patient-reported outcomes version of the common terminology criteria for adverse events (PRO-CTCAE™).
Annals of oncology : official journal of the European Society for Medical Oncology, 27 12
Shounak Majumder, Naoki Takahashi, Suresh Chari (2017)Autoimmune Pancreatitis
Digestive Diseases and Sciences, 62
J. George, Divyansh Bajaj, K. Sankaramangalam, J. Yoo, Nikhil Joshi, S. Gettinger, C. Price, J. Farrell (2019)Incidence of pancreatitis with the use of immune checkpoint inhibitors (ICI) in advanced cancers: A systematic review and meta-analysis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 19 4
Imad Majzoub, A. Qdaisat, K. Thein, M. Win, M. Han, K. Jacobson, Patrick Chaftari, M. Prejean, C. Reyes-Gibby, S. Yeung (2019)Adverse Effects of Immune Checkpoint Therapy in Cancer Patients Visiting the Emergency Department of a Comprehensive Cancer Center
Annals of Emergency Medicine, 73
H. Kaufman, J. Kirkwood, F. Hodi, S. Agarwala, T. Amatruda, S. Bines, Joseph Clark, B. Curti, M. Ernstoff, T. Gajewski, R. Gonzalez, Laura Hyde, D. Lawson, M. Lotze, J. Lutzky, K. Margolin, D. McDermott, D. Morton, A. Pavlick, J. Richards, W. Sharfman, V. Sondak, J. Sosman, S. Steel, A. Tarhini, John Thompson, J. Titze, W. Urba, R. White, M. Atkins (2013)The Society for Immunotherapy of Cancer consensus statement on tumour immunotherapy for the treatment of cutaneous melanoma
Nature Reviews Clinical Oncology, 10
G. Widmann, V. Nguyen, J. Plaickner, W. Jaschke (2017)Imaging Features of Toxicities by Immune Checkpoint Inhibitors in Cancer Therapy
Current Radiology Reports, 5
N. La‐Beck, G. Jean, Cindy Huynh, S. Alzghari, D. Lowe (2015)Immune Checkpoint Inhibitors: New Insights and Current Place in Cancer Therapy
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 35
S. Kiriyama, T. Gabata, T. Takada, K. Hirata, Masahiro Yoshida, T. Mayumi, M. Hirota, M. Kadoya, E. Yamanouchi, T. Hattori, K. Takeda, Y. Kimura, Hodaka Amano, K. Wada, M. Sekimoto, S. Arata, M. Yokoe, M. Hirota (2010)New diagnostic criteria of acute pancreatitis
Journal of Hepato-Biliary-Pancreatic Sciences, 17
Kamraan Madhani, J. Farrell (2016)Autoimmune Pancreatitis: An Update on Diagnosis and Management.
Gastroenterology clinics of North America, 45 1
L. Dehghani, N. Mikail, N. Kramkimel, P. Soyer, R. Lebtahi, R. Mallone, E. Larger (2018)Autoimmune pancreatitis after nivolumab anti-programmed death receptor-1 treatment.
European journal of cancer, 104
J. Weber, J. Yang, M. Atkins, M. Disis (2015)Toxicities of Immunotherapy for the Practitioner.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 33 18
J. Kwak, S. Tirumani, A. Abbeele, P. Koo, H. Jacene (2015)Cancer immunotherapy: imaging assessment of novel treatment response patterns and immune-related adverse events.
Radiographics : a review publication of the Radiological Society of North America, Inc, 35 2
R. Perez-Johnston, N. Sainani, D. Sahani (2012)Imaging of chronic pancreatitis (including groove and autoimmune pancreatitis).
Radiologic clinics of North America, 50 3
Sriluxayini Manikkavasakar, M. AlObaidy, Kiran Busireddy, M. Ramalho, Viragi Nilmini, Madhavi Alagiyawanna, R. Semelka (2014)Magnetic resonance imaging of pancreatitis: an update.
World journal of gastroenterology, 20 40
Weixun Zhou, Yan Huang, J. Lai, Jun Lu, Michael Feely, Xiuli Liu (2018)Anti-Inflammatory Biologics and Anti-Tumoral Immune Therapies-Associated Colitis: A Focused Review of Literature
Gastroenterology Research, 11
C. Johnson, M. Besselink, R. Carter (1988)Acute pancreatitis
BMJ : British Medical Journal, 349
M. Barral, B. Taouli, B. Guiu, Doh-Mu Koh, A. Luciani, R. Manfredi, V. Vilgrain, C. Hoeffel, M. Kanematsu, P. Soyer (2015)Diffusion-weighted MR imaging of the pancreas: current status and recommendations.
Radiology, 274 1
R. Badea (2005)Ultrasonography of acute pancreatitis -- an essay in images.
Romanian journal of gastroenterology, 14 1
C. Solinas, M. Aiello, P. Silva, C. Gu-Trantien, E. Migliori, K. Willard-Gallo (2019)Targeting PD-1 in cancer: Biological insights with a focus on breast cancer.
Critical reviews in oncology/hematology, 142
S. Grover, O. Rahma, N. Hashemi, Ramona Lim (2018)Gastrointestinal and Hepatic Toxicities of Checkpoint Inhibitors: Algorithms for Management.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 38
M. Postow (2015)Managing immune checkpoint-blocking antibody side effects.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
M. Smith (2012)Autoimmune Pancreatitis (AIP) Type 1 and Type 2: An International Consensus Study on Histopathologic Diagnostic Criteria
Yearbook of Pathology and Laboratory Medicine, 2012
The immunotherapy revolution in cancer treatment involves a variety of specialists, not only oncologists, but also internal medicine physicians, endocrinologists, dermatologists, gastroenterologists, rheumatologists, and radiologists, introducing new scenarios and novel challenges in the diagnosis and management of a number of novel immune-related adverse events. Among these, immune checkpoint inhibitor-induced pancreatic injury has been described (occurring in up to 4% of patients) and has been reported to be responsible for visits to the emergency departments in up to 1.9% of patients treated with immune checkpoint inhibitors. This side effect can be symptomatic or non-symptomatic, and can be associated with the development of long-term damage to the pancreas, requiring the involvement of different specialists, including radiologists and gastroenterologists in the multidisciplinary team that manages these patients. The aim of this narrative review is to provide a summary of the available literature related to immune checkpoint inhibitor-induced pancreatic injury including the epidemiology, the clinical findings, and the management algorithm for diagnosis with a detailed analysis of the differential diagnosis at imaging, and treatment. A more in-depth focus is dedicated to symptomatic acute pancreatitis with its peculiar findings at imaging (ultrasound, computed tomography, and magnetic resonance imaging).
Targeted Oncology – Springer Journals
Published: Feb 11, 2020
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