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Intensive Care for Emergency SurgeonsBlood Therapy in the Acute Care Surgery Patient

Intensive Care for Emergency Surgeons: Blood Therapy in the Acute Care Surgery Patient [Blood transfusion can be lifesaving, but it comes with a cost. Although viral disease transmission is no longer a major concern, transfusion-related immunomodulation is a real issue. Immunosuppression is associated with infections and cancer recurrence; hyperinflammation is associated with systemic inflammatory response syndrome, acute lung injury, and multiple organ failure. A restrictive approach to transfusion has been adopted for critically ill patients. Patients with acute coronary syndromes should have a higher transfusion threshold.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

Intensive Care for Emergency SurgeonsBlood Therapy in the Acute Care Surgery Patient

Part of the Hot Topics in Acute Care Surgery and Trauma Book Series
Editors: Picetti, Edoardo; Pereira, Bruno M.; Razek, Tarek; Narayan, Mayur; Kashuk, Jeffry L.
Biffl, Walter L.; Nasrallah, Fady
Intensive Care for Emergency Surgeons — May 30, 2019
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Publisher
Springer International Publishing
Copyright
© Springer Nature Switzerland AG 2019
ISBN
978-3-030-11829-7
Pages
181 –194
DOI
10.1007/978-3-030-11830-3_10
Publisher site
See Chapter on Publisher Site

Abstract

[Blood transfusion can be lifesaving, but it comes with a cost. Although viral disease transmission is no longer a major concern, transfusion-related immunomodulation is a real issue. Immunosuppression is associated with infections and cancer recurrence; hyperinflammation is associated with systemic inflammatory response syndrome, acute lung injury, and multiple organ failure. A restrictive approach to transfusion has been adopted for critically ill patients. Patients with acute coronary syndromes should have a higher transfusion threshold.]

Published: May 30, 2019

Keywords: Transfusion; Anticoagulation; Prothrombin complex concentrates; Direct oral anticoagulants; Novel oral anticoagulants

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