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Introducing Infectious Agents and Cancer

Introducing Infectious Agents and Cancer Infectious Agents and Cancer is a new open access, peer-reviewed, online journal, which encompasses all aspects of basic, clinical and translational research that provide an insight into the association between chronic infections and cancer. uncovered. The list has now expanded to include a com- Background Cancer has periodically been proposed as a transmissible mon bacterial pathogen (Helicobacter pylori infection with disease and specific pathogens have long been searched gastric carcinoma and mucosa-associated lymphoid tissue for. This proposition has been supported and confirmed [MALT] lymphoma) [6] as well as new viruses (hepatitis C in animal models, greatly contributing to our current virus [HCV] with liver cancer, human herpesvirus 6 with knowledge of biology, oncology, viral oncology, genetics, non-Hodgkin lymphoma, human herpesvirus 8 [also and other fields. Several Nobel prizes have been awarded known as KSHV] with Kaposi sarcoma [KS], Castleman for research in the field of infectious diseases and cancer, disease, and body cavity lymphomas) [7]. including those to Johannes Andreas Grib Fibiger (1926) [1]; Peyton Rous (1966) [2]; David Baltimore, Renato Although relevant literature points out the role of patho- Dulbecco and Howard M. Temin (1975) [3], and several gens in cancer and such studies have allowed fundamen- other studies have been of great relevance for the field. tal discoveries in cell biology as well as in pathogenetic mechanisms, nowadays cancer etiology, in the medical In 1991 Harald zur Hausen, who discovered in the early community at large, mainly refers to environmental 70's the association of HPV and cervical cancer, estimated chemical contamination or some genetic predisposition, that a significant fraction (~20%) of all human cancers losing the connotation of a disease associated with patho- worldwide are associated with infections due to viruses, gens and the possibility of a spreadable disease. Is this including human papillomaviruses (cervical cancer and right? other skin cancers), human T-lymphotropic viruses (adult T-cell leukemias and lymphomas in endemic areas), hep- Infectious Diseases and Cancer atitis B virus (liver cancer), and Epstein-Barr virus (Burkitt Worldwide 15 to 20% of cancers are linked to infectious lymphoma and nasopharyngeal carcinoma) [4,5]. This diseases [4,8]. In developed Western Countries approxi- estimate may now need to be further revised upward in mately 10% of all cancers are linked to infectious agents, light of the fact that new viral associations have been dis- but they account for as much as 20% of all cancers in covered and other non-viral associations have been developing countries. Such evidence contributed to the Page 1 of 3 (page number not for citation purposes) Infectious Agents and Cancer 2006, 1:1 http://www.infectagentscancer.com/content/1/1/1 major change in cancer pathogenetic studies with no fur- errors are introduced [9]. A copy of the full text of each ther search for specific cancer microbes, but with the iden- article is permanently archived in an online repository tification of the oncogenic role (in a minority of infected separate from the journal ensuring its permanence. individuals) of pathogens mainly ubiquitous in the gen- eral population. Within this new approach pathogen- Infectious Agents and Cancer articles are listed in PubMed related cancers have become a (final) stage in the progres- and are archived in PubMed Central [10], the US National sion of chronic infections with several scientific and prac- Library of Medicine's full-text repository of life science lit- tical consequences. Besides our increasing understanding erature, and also in repositories at the University of Pots- of the mechanism underlying cancer development, practi- dam [11] in Germany, at INIST [12] in France and in e- cal outcomes of these results are improved diagnosis and Depot [13], the National Library of the Netherlands' dig- identification of people at risk, the possibility to develop ital archive of all electronic publications. A further benefit specific therapeutic protocols for the respective tumors, of open access is that the published work will likely be and most remarkably for cancer prevention (i.e., the pre- read by more colleagues and will be cited more highly ventive value of early postnatal Hepatitis B vaccination in because of the easy availability [14]. regions with a high prevalence of Hepatitis B virus persist- ence). Finally, Infectious Agents and Cancer aims to become an exciting open forum for cancer research collecting and The results achieved thus far are very promising, but a few publishing the most innovative and significant work in major obstacles remain to be solved: in particular, the the cancer field. Such results will be achieved providing development of efficient therapeutic approaches for not only a fast, fair, and constructive review process, with chronic infections/cancer. Multidisciplinary approaches the valid support of an excellent editorial board, but also are needed in order to complement knowledge from sev- a dedicated team of scientific editors, who are willing to eral disciplines such microbiology/virology, immunol- discuss your research, respond to your pre-submission ogy, vaccinology, molecular biology, etc. in order to inquiries, and ensure that all manuscripts are reviewed on exploit new technologies (antigen identification, gene the basis of scientific merit and held to the highest stand- expression, antigen presentation, adjuvants' discovery and ards of excellence and editorial consistency. optimization, vaccine formulation, ex vivo DC activation, etc.). Closing Remarks We would like to take this opportunity to acknowledge Infectious Agents and Cancer objectives the Infectious Agents and Cancer Editorial Board http:// The results of relevant studies in the field should be made www.infectagentscancer.com/edboard/ for their commit- available to scientists and clinicians, in particular those in ment to the journal and to express our most sincere grati- developing countries where the fight against pathogen- tude to the entire staff of BioMed Central http:// related cancers is of the utmost importance. www.biomedcentral.com/ for their valuable advice and support in launching this journal. Infectious Agents and Cancer is a new open access, peer- reviewed, online journal, which encompasses all aspects We invite you to work together with us to develop this of basic, clinical and translational research that provide an new forum for infectious agents and cancer research, and insight into the association between chronic infections look forward to receiving your contributions, which will and cancer. The data will be published with unprece- help to make Infectious Agents and Cancer a scientific suc- dented immediacy. Every accepted manuscript will be cess. available for reading on its date of acceptance by any per- son who has access to the web. Formatted versions of the References 1. The Nobel Prize in Physiology or Medicine 1926. Presentation Speech by articles will follow, allowing readers to view the articles in Professor W. Wernstedt, Dean of the Royal Caroline Institute, December both web-friendly XML versions and typeset PDF versions 10, 1927, Nobel Lectures, Physiology or Medicine 1922–1941, Elsevier – ideal for printing out. Publishing Company, Amsterdam, 1965 . 2. Rous P: A sarcoma of the fowl transmissible by an agent sep- arable from the tumor cells. J Exp Med 1910, 12:696-705. The open access policy adopted by the journal, changes 3. The Nobel Prize in Physiology or Medicine 1975, Presentation Speech by the way in which articles are published. All articles are Professor Peter Reichard of the Karolinska Medico-Chirurgical Institute, From Nobel Lectures, Physiology or Medicine 1971–1980, Editor Jan Lind- freely and universally accessible online, and so an author's sten, World Scientific Publishing Co., Singapore, 1992 . work can be read by anyone at no cost. 4. zur Hausen H: Viruses in human cancers. Science 1991, 254:1167-1173. 5. zur Hausen H: Viruses in human tumors: reminiscences and Moreover, the author will hold copyright for his work and perspectives. Adv Cancer Res 1996, 68:1-22. grant anyone the right to reproduce and disseminate the 6. O'Connor F, Buckley M, O'Morain C: Helicobacter pylori: the cancer link. J R Soc Med 1993, 89:674-678. published article, provided that it is correctly cited and no Page 2 of 3 (page number not for citation purposes) Infectious Agents and Cancer 2006, 1:1 http://www.infectagentscancer.com/content/1/1/1 7. Persing DH, Prendergast FG: Infection, Immunity and Cancer. Arch Pathol Lab Med 1999, 123:1015-1022. 8. zur Hausen H: Oncogenic DNA viruses. Oncogene 2001, 20:7820-7823. 9. BioMed Central Open Access Charter [http://www.biomed central.com/info/about/charter] 10. PubMed Central [http://www.pubmedcentral.org] 11. Potsdam [http://www.uni-potsdam.de/over/homegd.htm] 12. INIST [http://www.inist.fr/] 13. e-Depot [http://www.kb.nl/] 14. Lawrence S: Free online availability substantially increases a paper's impact. Nature 2001, 411:521. Publish with Bio Med Central and every scientist can read your work free of charge "BioMed Central will be the most significant development for disseminating the results of biomedical researc h in our lifetime." Sir Paul Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep the copyright BioMedcentral Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp Page 3 of 3 (page number not for citation purposes) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Infectious Agents and Cancer Springer Journals

Introducing Infectious Agents and Cancer

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Publisher
Springer Journals
Copyright
Copyright © 2006 by Buonaguro et al; licensee BioMed Central Ltd.
Subject
Biomedicine; Cancer Research; Infectious Diseases; Oncology
eISSN
1750-9378
DOI
10.1186/1750-9378-1-1
pmid
23509916
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See Article on Publisher Site

Abstract

Infectious Agents and Cancer is a new open access, peer-reviewed, online journal, which encompasses all aspects of basic, clinical and translational research that provide an insight into the association between chronic infections and cancer. uncovered. The list has now expanded to include a com- Background Cancer has periodically been proposed as a transmissible mon bacterial pathogen (Helicobacter pylori infection with disease and specific pathogens have long been searched gastric carcinoma and mucosa-associated lymphoid tissue for. This proposition has been supported and confirmed [MALT] lymphoma) [6] as well as new viruses (hepatitis C in animal models, greatly contributing to our current virus [HCV] with liver cancer, human herpesvirus 6 with knowledge of biology, oncology, viral oncology, genetics, non-Hodgkin lymphoma, human herpesvirus 8 [also and other fields. Several Nobel prizes have been awarded known as KSHV] with Kaposi sarcoma [KS], Castleman for research in the field of infectious diseases and cancer, disease, and body cavity lymphomas) [7]. including those to Johannes Andreas Grib Fibiger (1926) [1]; Peyton Rous (1966) [2]; David Baltimore, Renato Although relevant literature points out the role of patho- Dulbecco and Howard M. Temin (1975) [3], and several gens in cancer and such studies have allowed fundamen- other studies have been of great relevance for the field. tal discoveries in cell biology as well as in pathogenetic mechanisms, nowadays cancer etiology, in the medical In 1991 Harald zur Hausen, who discovered in the early community at large, mainly refers to environmental 70's the association of HPV and cervical cancer, estimated chemical contamination or some genetic predisposition, that a significant fraction (~20%) of all human cancers losing the connotation of a disease associated with patho- worldwide are associated with infections due to viruses, gens and the possibility of a spreadable disease. Is this including human papillomaviruses (cervical cancer and right? other skin cancers), human T-lymphotropic viruses (adult T-cell leukemias and lymphomas in endemic areas), hep- Infectious Diseases and Cancer atitis B virus (liver cancer), and Epstein-Barr virus (Burkitt Worldwide 15 to 20% of cancers are linked to infectious lymphoma and nasopharyngeal carcinoma) [4,5]. This diseases [4,8]. In developed Western Countries approxi- estimate may now need to be further revised upward in mately 10% of all cancers are linked to infectious agents, light of the fact that new viral associations have been dis- but they account for as much as 20% of all cancers in covered and other non-viral associations have been developing countries. Such evidence contributed to the Page 1 of 3 (page number not for citation purposes) Infectious Agents and Cancer 2006, 1:1 http://www.infectagentscancer.com/content/1/1/1 major change in cancer pathogenetic studies with no fur- errors are introduced [9]. A copy of the full text of each ther search for specific cancer microbes, but with the iden- article is permanently archived in an online repository tification of the oncogenic role (in a minority of infected separate from the journal ensuring its permanence. individuals) of pathogens mainly ubiquitous in the gen- eral population. Within this new approach pathogen- Infectious Agents and Cancer articles are listed in PubMed related cancers have become a (final) stage in the progres- and are archived in PubMed Central [10], the US National sion of chronic infections with several scientific and prac- Library of Medicine's full-text repository of life science lit- tical consequences. Besides our increasing understanding erature, and also in repositories at the University of Pots- of the mechanism underlying cancer development, practi- dam [11] in Germany, at INIST [12] in France and in e- cal outcomes of these results are improved diagnosis and Depot [13], the National Library of the Netherlands' dig- identification of people at risk, the possibility to develop ital archive of all electronic publications. A further benefit specific therapeutic protocols for the respective tumors, of open access is that the published work will likely be and most remarkably for cancer prevention (i.e., the pre- read by more colleagues and will be cited more highly ventive value of early postnatal Hepatitis B vaccination in because of the easy availability [14]. regions with a high prevalence of Hepatitis B virus persist- ence). Finally, Infectious Agents and Cancer aims to become an exciting open forum for cancer research collecting and The results achieved thus far are very promising, but a few publishing the most innovative and significant work in major obstacles remain to be solved: in particular, the the cancer field. Such results will be achieved providing development of efficient therapeutic approaches for not only a fast, fair, and constructive review process, with chronic infections/cancer. Multidisciplinary approaches the valid support of an excellent editorial board, but also are needed in order to complement knowledge from sev- a dedicated team of scientific editors, who are willing to eral disciplines such microbiology/virology, immunol- discuss your research, respond to your pre-submission ogy, vaccinology, molecular biology, etc. in order to inquiries, and ensure that all manuscripts are reviewed on exploit new technologies (antigen identification, gene the basis of scientific merit and held to the highest stand- expression, antigen presentation, adjuvants' discovery and ards of excellence and editorial consistency. optimization, vaccine formulation, ex vivo DC activation, etc.). Closing Remarks We would like to take this opportunity to acknowledge Infectious Agents and Cancer objectives the Infectious Agents and Cancer Editorial Board http:// The results of relevant studies in the field should be made www.infectagentscancer.com/edboard/ for their commit- available to scientists and clinicians, in particular those in ment to the journal and to express our most sincere grati- developing countries where the fight against pathogen- tude to the entire staff of BioMed Central http:// related cancers is of the utmost importance. www.biomedcentral.com/ for their valuable advice and support in launching this journal. Infectious Agents and Cancer is a new open access, peer- reviewed, online journal, which encompasses all aspects We invite you to work together with us to develop this of basic, clinical and translational research that provide an new forum for infectious agents and cancer research, and insight into the association between chronic infections look forward to receiving your contributions, which will and cancer. The data will be published with unprece- help to make Infectious Agents and Cancer a scientific suc- dented immediacy. Every accepted manuscript will be cess. available for reading on its date of acceptance by any per- son who has access to the web. Formatted versions of the References 1. The Nobel Prize in Physiology or Medicine 1926. Presentation Speech by articles will follow, allowing readers to view the articles in Professor W. Wernstedt, Dean of the Royal Caroline Institute, December both web-friendly XML versions and typeset PDF versions 10, 1927, Nobel Lectures, Physiology or Medicine 1922–1941, Elsevier – ideal for printing out. Publishing Company, Amsterdam, 1965 . 2. Rous P: A sarcoma of the fowl transmissible by an agent sep- arable from the tumor cells. J Exp Med 1910, 12:696-705. The open access policy adopted by the journal, changes 3. The Nobel Prize in Physiology or Medicine 1975, Presentation Speech by the way in which articles are published. All articles are Professor Peter Reichard of the Karolinska Medico-Chirurgical Institute, From Nobel Lectures, Physiology or Medicine 1971–1980, Editor Jan Lind- freely and universally accessible online, and so an author's sten, World Scientific Publishing Co., Singapore, 1992 . work can be read by anyone at no cost. 4. zur Hausen H: Viruses in human cancers. Science 1991, 254:1167-1173. 5. zur Hausen H: Viruses in human tumors: reminiscences and Moreover, the author will hold copyright for his work and perspectives. Adv Cancer Res 1996, 68:1-22. grant anyone the right to reproduce and disseminate the 6. O'Connor F, Buckley M, O'Morain C: Helicobacter pylori: the cancer link. J R Soc Med 1993, 89:674-678. published article, provided that it is correctly cited and no Page 2 of 3 (page number not for citation purposes) Infectious Agents and Cancer 2006, 1:1 http://www.infectagentscancer.com/content/1/1/1 7. Persing DH, Prendergast FG: Infection, Immunity and Cancer. Arch Pathol Lab Med 1999, 123:1015-1022. 8. zur Hausen H: Oncogenic DNA viruses. Oncogene 2001, 20:7820-7823. 9. BioMed Central Open Access Charter [http://www.biomed central.com/info/about/charter] 10. PubMed Central [http://www.pubmedcentral.org] 11. Potsdam [http://www.uni-potsdam.de/over/homegd.htm] 12. INIST [http://www.inist.fr/] 13. e-Depot [http://www.kb.nl/] 14. Lawrence S: Free online availability substantially increases a paper's impact. Nature 2001, 411:521. Publish with Bio Med Central and every scientist can read your work free of charge "BioMed Central will be the most significant development for disseminating the results of biomedical researc h in our lifetime." Sir Paul Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep the copyright BioMedcentral Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp Page 3 of 3 (page number not for citation purposes)

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Infectious Agents and Cancer – Springer Journals

Published: Sep 14, 2006

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