Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Investigation and analysis of osteoporosis, falls, and fragility fractures in elderly people in the Beijing area: a study on the bone health status of elderly people ≥ 80 years old with life self-care

Investigation and analysis of osteoporosis, falls, and fragility fractures in elderly people in... Abstract Summary Among ≥ 80 years old and under life self-care in the Beijing area, the prevalences of osteoporosis, falls, and fragility fracture were high; and these prevalences were even higher in women. The treatment rate of osteoporosis is very low. Therefore, comprehensive and standardized prevention and treatment should be promoted. Purpose The purpose of this study is to investigate prevalence of osteoporosis, falls, and fragility fractures in this population, and analyze related factors, in order to provide a basis for standardized prevention and treatment. Methods From August 2015 to August 2016 in Beijing City, a total of 175 elderly individuals, who were ≥ 80 years old and had good self-care ability, were included into this study. The questionnaire, risk of falls, grip force, and walking speed were measured, and the Timed Up and Go test (TUG) and chair-rising test (CRT) were performed. Results Compared to women, men have higher rates of smoking, drinking, drinking strong tea, longer outdoor activity time, as well as larger muscle strength and pace, and lower consumption of dairy products, fall risk assessment scale (FRA) score, 25OHD, administration rates of calcium and anti-osteoporosis drugs (P < 0.05, P < 0.01). Compared with men, women had higher bone turnover markers (P1NP, β-CTx, and OC) (P < 0.05, P < 0.01) and lower levels of sex hormones (E2, T) (P < 0.01). The overall prevalence of osteoporosis was 24.6%, and this was significantly higher in women than in men (52.5 vs. 9.6%, P < 0.01). Among these subjects, 62.9% had a history of fall after 80 years old, and this rate was higher in women than in men (77 vs. 55.3%, P < 0.01). The overall prevalence of fragility fractures was 25.1%, which was higher in women than in men (45.9 vs. 14.0%, P < 0.01). Risk factors included falls after age 80, high FRA score, and reduction in bone density of lumbar vertebrae 1–4, and odds ratio (OR) was 12.195, 1.339, and 0.076, respectively (P < 0.01). Anti-osteoporosis therapy was only performed on a small number of patients with fractures. Conclusion The prevalences of falls, prior fracture, and low BMD were high among ≥ 80 years old and under life self-care in the Beijing area. Therefore, a comprehensive approach to assessment and treatment should be promoted. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Osteoporosis Springer Journals

Investigation and analysis of osteoporosis, falls, and fragility fractures in elderly people in the Beijing area: a study on the bone health status of elderly people ≥ 80 years old with life self-care

Download PDF
8 pages

Loading next page...
 
/lp/springer-journals/investigation-and-analysis-of-osteoporosis-falls-and-fragility-ke5ONUfgOg
Publisher
Springer Journals
Copyright
2017 International Osteoporosis Foundation and National Osteoporosis Foundation
ISSN
1862-3522
eISSN
1862-3514
DOI
10.1007/s11657-017-0408-2
Publisher site
See Article on Publisher Site

Abstract

Abstract Summary Among ≥ 80 years old and under life self-care in the Beijing area, the prevalences of osteoporosis, falls, and fragility fracture were high; and these prevalences were even higher in women. The treatment rate of osteoporosis is very low. Therefore, comprehensive and standardized prevention and treatment should be promoted. Purpose The purpose of this study is to investigate prevalence of osteoporosis, falls, and fragility fractures in this population, and analyze related factors, in order to provide a basis for standardized prevention and treatment. Methods From August 2015 to August 2016 in Beijing City, a total of 175 elderly individuals, who were ≥ 80 years old and had good self-care ability, were included into this study. The questionnaire, risk of falls, grip force, and walking speed were measured, and the Timed Up and Go test (TUG) and chair-rising test (CRT) were performed. Results Compared to women, men have higher rates of smoking, drinking, drinking strong tea, longer outdoor activity time, as well as larger muscle strength and pace, and lower consumption of dairy products, fall risk assessment scale (FRA) score, 25OHD, administration rates of calcium and anti-osteoporosis drugs (P < 0.05, P < 0.01). Compared with men, women had higher bone turnover markers (P1NP, β-CTx, and OC) (P < 0.05, P < 0.01) and lower levels of sex hormones (E2, T) (P < 0.01). The overall prevalence of osteoporosis was 24.6%, and this was significantly higher in women than in men (52.5 vs. 9.6%, P < 0.01). Among these subjects, 62.9% had a history of fall after 80 years old, and this rate was higher in women than in men (77 vs. 55.3%, P < 0.01). The overall prevalence of fragility fractures was 25.1%, which was higher in women than in men (45.9 vs. 14.0%, P < 0.01). Risk factors included falls after age 80, high FRA score, and reduction in bone density of lumbar vertebrae 1–4, and odds ratio (OR) was 12.195, 1.339, and 0.076, respectively (P < 0.01). Anti-osteoporosis therapy was only performed on a small number of patients with fractures. Conclusion The prevalences of falls, prior fracture, and low BMD were high among ≥ 80 years old and under life self-care in the Beijing area. Therefore, a comprehensive approach to assessment and treatment should be promoted.

Journal

Archives of Osteoporosis – Springer Journals

Published: Dec 1, 2017

References

  • The diagnosis of osteoporosis
    JA Kanis, LJ Melton, C Christiansen, CC Johnston, N Khaltaev
  • Fear of falling, fracture history, and comorbidities are associated with health-related quality of life among European and US women with osteoporosis in a large international study
    F Guillemin, L Martinez, M Calvert, C Cooper, T Ganiats
  • UK Biobank Musculoskeletal Advisory Group. Osteoporosis epidemiology in UK Biobank: a unique opportunity for international researchers
    NC Harvey, P Matthews, R Collins, C Cooper
  • [webpage on the Internet]
    National economic and social development statistical bulletin
  • Epidemiology of primary osteoporosis in China
    ZH Liu, YL Zhao, GZ Ding, Y Zhou
  • Rapidly increasing rates of hip fracture in Beijing, China
    WB Xia, SL He, L Xu, AM Liu, Y Jiang, M Li, O Wang, XP Xing, Y Sun, SR Cummings
  • A population-based study examining calcaneus quantitative ultrasound and its optimal cut-points to discriminate osteoporotic fractures among 9352 Chinese women and men
    JM Liu, LY Ma, YF Bi, Y Xu, Y Huang
  • Health technology assessment in osteoporosis
    M Hiligsmann, JA Kanis, J Compston, C Cooper, B Flamion, P Bergmann, JJ Body, S Boonen, O Bruyere, JP Devogelaer, S Goemaere, JM Kaufman, S Rozenberg, JY Reginster
  • Management of osteoporosis of the oldest old
    R Rizzoli, J Branco, M-L Brandi, S Boonen, O Bruyère, P Cacoub, C Cooper, A Diez-Perez, J Duder, RA Fielding, NC Harvey, M Hiligsmann, JA Kanis, J Petermans, JD Ringe, Y Tsouderos, J Weinman, J-Y Reginster
  • Epidemiology and management of osteoporosis in the People’s Republic of China: current perspectives
    X Lin, D Xiong, Y-Q Peng, Z-F Sheng, X-Y Wu, X-P Wu, F Wu, L-Q Yuan, E-Y Liao
  • Guidelines for diagnosis and treatment of primary osteoporosis
  • Prevalence rate of osteoporosis in themid- aged and elderly in selected parts of China
    N Li, P Ou, H Zhu, D Yang, P Zheng
  • Age-related bone mineral density, bone loss rate, prevalence of osteoporosis, and reference database of women at multiple centers in China
    XG Cheng, DZ Yang, Q Zhou, TJ Zhuo, HC Zhang, J Xiang, HF Wang, PZ Ou, JL Liu, L Xu, JY Huang, QR Huang, HS Barden, LS Weynand, KG Faulkner, XW Meng
  • Effects of estrogen with micronized progesterone on cortical and trabecular bone mass and microstructure in recently postmenopausal women
    JN Farr, S Khosla, Y Miyabara, VM Miller, AE Kearns
  • Estradiol levels predict bone mineral density in male collegiate athletes: a pilot study
    KE Ackerman, GS Skrinar, E Medvedova, M Misra, KK Miller
  • Factors associated with lumbar bone mineral density in old-aged men
    QF Ying, PD Bian, XY Li, JP Chen
  • Androgen-deprivation-associated bone disease
    AS Ted, VC Megan, BS Vahakn
  • Sarcopenia and its relationship with bone mineral density in middle-age and elderly European men
    S Verschueren, E Gilelen, TW O'Neill, SR Pye, JE Adams, KA Ward, FC Wu, P Szulc, M Laurent, F Claessens, D Vanderschueren, S Boonen
  • Epidemiology of adrenal insufficiency: a nationwide study of hospitalizations in Taiwan from 1996 to 2008
    YC Chen, YH Lin, SH Chen, Y-C Chen, LF Chou, TJ Chen, SJ Hwang
  • An update on selective estrogen receptor modulators for the prevention and treatment of osteoporosis
    BS Komm, AA Chines
  • Guidelines for the prevention of falls in people over 65. The Guidelines, Development Group
    G Feder, C Cryer, S Donovan, Y Carter
  • Interventions for preventing falls in older people living in the community (Review)
    LD Gillespie, MC Robertson, WJ Gillespie, SE Lamb, S Gates
  • Predictors of falls among postmenopausal women: results from the National Osteoporosis Risk Assessment (NORA)
    E Barrett-Connor, TW Weiss, CA McHorney, PD Miller, S Siries
  • Shifting the focus in fracture prevention from osteoporosis to falls
    TL Järvinen, H Sievänen, KM Khan, A Heinonen, P Kannus
  • Decreased lower limb muscle recruitment contributes to the inability of older adults to recover with a single step following a forward loss of balance
    NJ Cronin, RS Barrett, G Lichtwark, PM Mills, CP Carty
  • Fractures attributable to osteoporosis: report from the National Osteoporosis Foundation
    LJ Melton, M Thamer, NF Ray, JK Chan, CH Chesnut, TA Einhorn, CC Johnston, LG Raisz, SL Silverman, ES Siris
  • A survey of outcomes and management of patients post fragility fractures in China
    O Wang, Y Hu, S Gong, Q Xue, Z Deng, L Wang, H Liu, H Tang