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Micro and Smart Devices and SystemsDevelopment of a Surface Plasmon Resonance-Based Biosensing System

Micro and Smart Devices and Systems: Development of a Surface Plasmon Resonance-Based Biosensing... [Surface Plasmon Resonance (SPR)-based biosensing systems have become very popular among biologists and biochemists due to their ability to sense biomolecular interaction kinetics. It can be easily surmised that such systems may be of great use in diagnostic applications as well. However, the principal impediment to wide-scale deployment of these devices is the cost of the instrument. This effort to develop a low cost, widely deployable instrument was born out of a desire to initially popularize this instrument and technique among colleges and universities with budget constraints and move toward developing diagnostic applications on this platform. A low-cost device with significant sensitivity was developed, and this chapter describes the development on this front.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

Micro and Smart Devices and SystemsDevelopment of a Surface Plasmon Resonance-Based Biosensing System

Part of the Springer Tracts in Mechanical Engineering Book Series
Editors: Vinoy, K. J.; Ananthasuresh, G. K.; Pratap, Rudra; Krupanidhi, S. B.
Mukherji, S.; Hossain, Munshi Imran; Kundu, T.; Chandratre, Deepali
Micro and Smart Devices and Systems — May 22, 2014
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Publisher
Springer India
Copyright
© Springer India 2014
ISBN
978-81-322-1912-5
Pages
49 –72
DOI
10.1007/978-81-322-1913-2_4
Publisher site
See Chapter on Publisher Site

Abstract

[Surface Plasmon Resonance (SPR)-based biosensing systems have become very popular among biologists and biochemists due to their ability to sense biomolecular interaction kinetics. It can be easily surmised that such systems may be of great use in diagnostic applications as well. However, the principal impediment to wide-scale deployment of these devices is the cost of the instrument. This effort to develop a low cost, widely deployable instrument was born out of a desire to initially popularize this instrument and technique among colleges and universities with budget constraints and move toward developing diagnostic applications on this platform. A low-cost device with significant sensitivity was developed, and this chapter describes the development on this front.]

Published: May 22, 2014

Keywords: Surface plasmon resonance; Biosensor; Biomolecular interaction; Immobilization of antibodies; Optical detection

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