Access the full text.
Sign up today, get DeepDyve free for 14 days.
E. Small, L. Sutherland, Kartik Rajagopalan, Shusheng Wang, E. Olson (2010)MicroRNA-218 Regulates Vascular Patterning by Modulation of Slit-Robo Signaling
Circulation Research, 107
E. Lee, Yuriy Gusev, Jinmai Jiang, G. Nuovo, M. Lerner, W. Frankel, D. Morgan, R. Postier, D. Brackett, Thomas Schmittgen (2006)Expression profiling identifies microRNA signature in pancreatic cancer
International Journal of Cancer, 120
Shuomin Zhu, M-L Si, Hailong Wu, Y. Mo (2007)MicroRNA-21 Targets the Tumor Suppressor Gene Tropomyosin 1 (TPM1)*
Journal of Biological Chemistry, 282
Xiaoxiao Hu, J. Schwarz, J. Lewis, P. Huettner, J. Rader, J. Deasy, P. Grigsby, Xiaowei Wang (2010)A microRNA expression signature for cervical cancer prognosis.
Cancer research, 70 4
Jeong-Won Lee, C. Choi, Jung-Joo Choi, Y. Park, Seung-Jun Kim, S. Hwang, W. Kim, Tae-Joong Kim, Je‐ho Lee, Byoung-Gie Kim, D. Bae (2008)Altered MicroRNA Expression in Cervical Carcinomas
Clinical Cancer Research, 14
D. Parkin, F. Bray, J. Ferlay, P. Pisani (2005)Global Cancer Statistics, 2002
CA: A Cancer Journal for Clinicians, 55
A. Bernards, J. Settleman (2009)Loss of the Ras regulator RASAL1: another route to Ras activation in colorectal cancer.
Gastroenterology, 136 1
Nga Nguyen, A. Kuliopulos, R. Graham, L. Covic (2006)Tumor-derived Cyr61(CCN1) promotes stromal matrix metalloproteinase-1 production and protease-activated receptor 1-dependent migration of breast cancer cells.
Cancer research, 66 5
De-Wei Wu, Ya‐Wen Cheng, John Wang, Chih‐Yi Chen, Hue Lee (2010)Paxillin predicts survival and relapse in non-small cell lung cancer by microRNA-218 targeting.
Cancer research, 70 24
V. Ambros (2004)The functions of animal microRNAs
(2010)Magee-Women's Hospital of the University of Pittsburgh Medical Center
Wang Lp, J. Bi, C. Yao, Xu Xd, Li Xx, Wang Sm, Li Zl, Zhang Dy, M. Wang, Chang Gq (2010)Annexin A1 expression and its prognostic significance in human breast cancer.
Neoplasma, 57 3
A. Jemal, F. Bray, Melissa Center, J. Ferlay, Elizabeth Ward, D. Forman (2011)Global cancer statistics
CA: A Cancer Journal for Clinicians, 61
Q. Yao, Hui Xu, Qian-Qian Zhang, Hui Zhou, L. Qu (2009)MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells.
Biochemical and biophysical research communications, 388 3
M. Iorio, R. Visone, Gianpiero Leva, V. Donati, F. Petrocca, P. Casalini, C. Taccioli, S. Volinia, Chang-gong Liu, H. Alder, G. Calin, S. Ménard, C. Croce (2007)MicroRNA signatures in human ovarian cancer.
Cancer research, 67 18
Shuomin Zhu, Hailong Wu, Fangting Wu, D. Nie, S. Sheng, Y. Mo (2008)MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
Cell Research, 18
M. Manos, J. Waldman, T. Zhang, C. Greer, G. Eichinger, M. Schiffman, C. Wheeler (1994)Epidemiology and partial nucleotide sequence of four novel genital human papillomaviruses.
The Journal of infectious diseases, 170 5
Kati Porkka, Minja Pfeiffer, Kati Waltering, R. Vessella, T. Tammela, T. Visakorpi (2007)MicroRNA expression profiling in prostate cancer.
Cancer research, 67 13
(2009)Down-regulated miR9 and miR-433 in human gastric carcinoma
S. Chellappan, V. Kraus, B. Kroger, Karl MUNGERt, Peter HOWLEYt, W. Phelps, J. Nevins (1992)Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.
Proceedings of the National Academy of Sciences of the United States of America, 89
Xiaohong Wang, Shuāng Táng, S. Le, Robert Lu, J. Rader, C. Meyers, Zhi-Ming Zheng (2008)Aberrant Expression of Oncogenic and Tumor-Suppressive MicroRNAs in Cervical Cancer Is Required for Cancer Cell Growth
PLoS ONE, 3
J. Tie, Yanglin Pan, Lina Zhao, Kaichun Wu, Jie Liu, Shiren Sun, Xuegang Guo, Biao-luo Wang, Yi Gang, Yongguo Zhang, Quanjiang Li, T. Qiao, Qingchuan Zhao, Y. Nie, D. Fan (2010)MiR-218 Inhibits Invasion and Metastasis of Gastric Cancer by Targeting the Robo1 Receptor
PLoS Genetics, 6
G. Calin, A. Cimmino, M. Fabbri, M. Ferracin, Sylwia Wojcik, M. Shimizu, C. Taccioli, N. Zanesi, R. Garzon, R. Aqeilan, H. Alder, S. Volinia, L. Rassenti, Xiuping Liu, Chang-gong Liu, T. Kipps, M. Negrini, C. Croce (2008)MiR-15a and miR-16-1 cluster functions in human leukemia
Proceedings of the National Academy of Sciences, 105
S. Gery, D. Xie, D. Yin, H. Gabra, C. Miller, He Wang, D. Scott, W. Yi, M. Popoviciu, J. Said, H. Koeffler (2005)Ovarian Carcinomas: CCN Genes Are Aberrantly Expressed and CCN1 Promotes Proliferation of these Cells
Clinical Cancer Research, 11
M. Tennis, M. Scoyk, S. Freeman, K. Vandervest, R. Nemenoff, R. Winn (2010)Sprouty-4 Inhibits Transformed Cell Growth, Migration and Invasion, and Epithelial-Mesenchymal Transition, and Is Regulated by Wnt7A through PPARγ in Non–Small Cell Lung Cancer
Molecular Cancer Research, 8
A. Jemal, F. Bray, Melissa Center, J. Ferlay, Elizabeth Ward, David Forman (2011)Global Cancer Statistics
Jinmai Jiang, Yuriy Gusev, Ileana Aderca, Teresa Mettler, D. Nagorney, D. Brackett, L. Roberts, Thomas Schmittgen (2008)Association of MicroRNA Expression in Hepatocellular Carcinomas with Hepatitis Infection, Cirrhosis, and Patient Survival
Clinical Cancer Research, 14
W. Lui, N. Pourmand, B. Patterson, A. Fire (2007)Patterns of known and novel small RNAs in human cervical cancer.
Cancer research, 67 13
J. Walboomers, M. Jacobs, M. Manos, F. Bosch, J. Kummer, K. Shah, P. Snijders, J. Peto, C. Meijer, N. Muñoz (1999)Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
The Journal of Pathology, 189
G. Calin, C. Sevignani, C. Dumitru, T. Hyslop, E. Noch, S. Yendamuri, M. Shimizu, S. Rattan, F. Bullrich, M. Negrini, C. Croce (2004)Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers.
Proceedings of the National Academy of Sciences of the United States of America, 101 9
Werness Ba, A. Levine, P. Howley (1990)Association of human papillomavirus types 16 and 18 E6 proteins with p53.
Science, 248 4951
E. Villiers, C. Fauquet, T. Broker, H. Bernard, H. Hausen (2004)Classification of papillomaviruses.
Virology, 324 1
Xiaoyi Zhou, Xiaojun Chen, Lingmin Hu, Suping Han, Fulin Qiang, Yu-lin Wu, L. Pan, Hongbing Shen, Y. Li, Zhibin Hu (2010)Polymorphisms involved in the miR-218-LAMB3 pathway and susceptibility of cervical cancer, a case-control study in Chinese women.
Gynecologic oncology, 117 2
H. Hausen (2002)Papillomaviruses and cancer: from basic studies to clinical application
Nature Reviews Cancer, 2
F. Petrocca, R. Visone, Mariadele Onelli, M. Shah, M. Nicoloso, Ivana Martino, D. Iliopoulos, E. Pilozzi, Chang-gong Liu, M. Negrini, L. Cavazzini, S. Volinia, H. Alder, L. Ruco, G. Baldassarre, C. Croce, A. Vecchione (2008)E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer.
Cancer cell, 13 3
H. Wan, Ming Yuan, C. Simpson, K. Allen, F. Gavins, M. Ikram, S. Basu, N. Baksh, E. O’Toole, I. Hart (2007)Stem/Progenitor Cell‐Like Properties of Desmoglein 3dim Cells in Primary and Immortalized Keratinocyte Lines
STEM CELLS, 25
M. Buim, F. Soares, Á. Sarkis, M. Nagai (2006)The Transcripts of SFRP1,CEP63 and EIF4G2 Genes Are Frequently Downregulated in Transitional Cell Carcinomas of the Bladder
Liming Zhang, Tan Deng, Xiayu Li, Hua-ying Liu, Hou-de Zhou, Jian Ma, Minghua Wu, M. Zhou, S. Shen, Xiaoling Li, Zhaoxia Niu, Wenling Zhang, Lei Shi, Bo Xiang, Jianhong Lu, Li Wang, Dan Li, Hailin Tang, Gui-yuan Li (2010)microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network.
Carcinogenesis, 31 4
G. Calin, C. Dumitru, M. Shimizu, R. Bichi, S. Zupo, E. Noch, Hansjuerg Aldler, S. Rattan, M. Keating, K. Rai, L. Rassenti, T. Kipps, M. Negrini, F. Bullrich, C. Croce (2002)Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
Proceedings of the National Academy of Sciences of the United States of America, 99
E. Bandrés, E. Cubedo, X. Agirre, R. Malumbres, R. Zárate, N. Ramirez, A. Abajo, A. Navarro, I. Moreno, M. Monzó, J. García-Foncillas (2006)Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues
Molecular Cancer, 5
Lin Zhang, Jia Huang, N. Yang, J. Greshock, M. Megraw, Antonis Giannakakis, Shun Liang, Tara Naylor, A. Barchetti, M. Ward, G. Yao, Angelica Medina, A. O’Brien-Jenkins, D. Katsaros, A. Hatzigeorgiou, P. Gimotty, B. Weber, G. Coukos (2006)microRNAs exhibit high frequency genomic alterations in human cancer.
Proceedings of the National Academy of Sciences of the United States of America, 103 24
A. Cimmino, G. Calin, M. Fabbri, M. Iorio, M. Ferracin, M. Shimizu, Sylwia Wojcik, R. Aqeilan, S. Zupo, M. Dono, L. Rassenti, H. Alder, S. Volinia, Chang-gong Liu, T. Kipps, M. Negrini, C. Croce (2005)miR-15 and miR-16 induce apoptosis by targeting BCL2.
Proceedings of the National Academy of Sciences of the United States of America, 102 39
R. Davies, R. Hicks, T. Crook, '. Morris, Karen VOUSDENl (1993)Human papillomavirus type 16 E7 associates with a histone H1 kinase and with p107 through sequences necessary for transformation
Journal of Virology, 67
J. Takamizawa, H. Konishi, K. Yanagisawa, S. Tomida, H. Osada, H. Endoh, T. Harano, Y. Yatabe, M. Nagino, Y. Nimura, T. Mitsudomi, Takashi Takahashi (2004)Reduced Expression of the let-7 MicroRNAs in Human Lung Cancers in Association with Shortened Postoperative Survival
Cancer Research, 64
A. Jemal, R. Siegel, Jiaquan Xu, Elizabeth Ward (2010)Cancer Statistics, 2010
CA: A Cancer Journal for Clinicians, 60
T. Araki, J. Milbrandt (2000)Ninjurin2, a Novel Homophilic Adhesion Molecule, Is Expressed in Mature Sensory and Enteric Neurons and Promotes Neurite Outgrowth
The Journal of Neuroscience, 20
Xiaohong Wang, Hsu-kun Wang, J. McCoy, N. Banerjee, J. Rader, T. Broker, C. Meyers, L. Chow, Zhi-Ming Zheng (2009)Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6.
RNA, 15 4
C. Bracken, P. Gregory, Natasha Kolesnikoff, A. Bert, Jun Wang, M. Shannon, G. Goodall (2008)A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition.
Cancer research, 68 19
R. Katzenellenbogen, Portia Vliet-Gregg, Mei Xu, D. Galloway (2010)Cytoplasmic Poly(A) Binding Proteins Regulate Telomerase Activity and Cell Growth in Human Papillomavirus Type 16 E6-Expressing Keratinocytes
Journal of Virology, 84
G. Ho, R. Bierman, L. Beardsley, C. Chang, R. Burk (1998)Natural history of cervicovaginal papillomavirus infection in young women.
The New England journal of medicine, 338 7
J. Huibregtse, M. Scheffner, P. Howley (1991)A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18.
The EMBO Journal, 10
M. Pett, W. Alazawi, I. Roberts, S. Dowen, David Smith, M. Stanley, N. Coleman (2004)Acquisition of High-Level Chromosomal Instability Is Associated with Integration of Human Papillomavirus Type 16 in Cervical Keratinocytes
Cancer Research, 64
Junming Guo, Ying Miao, B. Xiao, Rong Huan, Zhen Jiang, D. Meng, Yanjun Wang (2009)Differential expression of microRNA species in human gastric cancer versus non‐tumorous tissues
Journal of Gastroenterology and Hepatology, 24
F. Meng, R. Henson, H. Wehbe-Janek, K. Ghoshal, S. Jacob, T. Patel (2007)MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer.
Gastroenterology, 133 2
A. Klingelhutz, S. Foster, J. McDougall (1996)Telomerase activation by the E6 gene product of human papillomavirus type 16
Baohua Li, Ying Hu, F. Ye, Yang Li, W. Lv, Xing Xie (2010)Reduced miR-34a Expression in Normal Cervical Tissues and Cervical Lesions With High-Risk Human Papillomavirus Infection
International Journal of Gynecologic Cancer, 20
T. Kaddar, J. Rouault, W. Chien, A. Chebel, M. Gadoux, G. Salles, M. Ffrench, J. Magaud (2009)Two new miR‐16 targets: caprin‐1 and HMGA1, proteins implicated in cell proliferation
Biology of the Cell, 101
Holger Zimmermann, Roland Degenkolbe, H. Bernard, M. O’Connor (1999)The Human Papillomavirus Type 16 E6 Oncoprotein Can Down-Regulate p53 Activity by Targeting the Transcriptional Coactivator CBP/p300
Journal of Virology, 73
M. Bellon, Y. Lepelletier, O. Hermine, C. Nicot (2009)Deregulation of microRNA involved in hematopoiesis and the immune response in HTLV-I adult T-cell leukemia.
Blood, 113 20
E. Mathé, G. Nguyen, E. Bowman, Yiqiang Zhao, A. Budhu, Aaron Schetter, R. Braun, M. Reimers, K. Kumamoto, Duncan Hughes, N. Altorki, A. Casson, Chang Liu, X. Wang, N. Yanaihara, N. Hagiwara, A. Dannenberg, M. Miyashita, C. Croce, C. Harris (2009)MicroRNA Expression in Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus: Associations with Survival
Clinical Cancer Research, 15
S. Balsitis, F. Dick, N. Dyson, P. Lambert (2006)Critical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesis.
Cancer research, 66 19
D. Patel, Shih-Min Huang, L. Baglia, D. McCance (1999)The E6 protein of human papillomavirus type 16 binds to and inhibits co‐activation by CBP and p300
The EMBO Journal, 18
Acog (2005)ACOG practice bulletin. Clinical management guidelines of obstetrician-gynecologists. Number 67, October 2005. Medical management of abortion.
Obstetrics & Gynecology, 106
K. Farh, Andrew Grimson, Calvin Jan, B. Lewis, W. Johnston, Lee Lim, C. Burge, D. Bartel (2005)The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution
Caiping Gao, Zhi-yu Zhang, Wenzhong Liu, S. Xiao, Weiqi Gu, Hong Lu (2009)Reduced microRNA‐218 expression is associated with high nuclear factor kappa B activation in gastric cancer
Miranda Thomas, D. Pim, L. Banks (1999)The role of the E6-p53 interaction in the molecular pathogenesis of HPV
L. Lim, S. Pervaiz (2007)Annexin 1: the new face of an old molecule
The FASEB Journal, 21
Patrícia Pereira, João Marques, A. Soares, L. Carreto, Manuel Santos (2010)MicroRNA Expression Variability in Human Cervical Tissues
PLoS ONE, 5
N. Dyson, P. Howley, K. Münger, E. Harlow (1989)The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product.
Science, 243 4893
K. Livak, Thomas Schmittgen (2001)Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.
Methods, 25 4
E. Nam, Heejei Yoon, Sang Kim, Hoguen Kim, Young Kim, Jae Kim, J. Kim, Sunghoon Kim (2008)MicroRNA Expression Profiles in Serous Ovarian Carcinoma
Clinical Cancer Research, 14
(2005)Clinical Management Guidelines for Obstetrician-Gynecologists. Human papillomavirus
J. Chai, M. Norng, C. Modak, K. Reavis, W. Mouazzen, J. Pham (2010)CCN1 induces a reversible epithelial–mesenchymal transition in gastric epithelial cells
Laboratory Investigation, 90
Maritza Mcintyre, M. Ruesch, L. Laimins (1996)Human papillomavirus E7 oncoproteins bind a single form of cyclin E in a complex with cdk2 and p107.
Virology, 215 1
Zuozhen Yang, Shuang Chen, Xuejing Luan, Yi-xuan Li, Min Liu, Xin Li, Tao Liu, Hua Tang (2009)MicroRNA‐214 is aberrantly expressed in cervical cancers and inhibits the growth of HeLa cells
IUBMB Life, 61
S. Griffiths-Jones, H. Saini, S. Dongen, Anton Enright (2007)miRBase: tools for microRNA genomics
Nucleic Acids Research, 36
U. Burk, Jörg Schubert, U. Wellner, O. Schmalhofer, E. Vincan, S. Spaderna, T. Brabletz (2008)A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
EMBO Reports, 9
S. Duensing, L. Lee, A. Duensing, J. Basile, Siribang-on Piboonniyom, Sonia Gonzalez, C. Crum, K. Münger (2000)The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle.
Proceedings of the National Academy of Sciences of the United States of America, 97 18
Ying Wang, Xiao Zhang, Bao-feng Zhang, Chang-qing Yang, Xi Chen, Heng-jun Gao (2010)Initial study of microRNA expression profiles of colonic cancer without lymph node metastasis
Journal of Digestive Diseases, 11
Ivan Martinez, A. Gardiner, K. Board, F. Monzon, R. Edwards, S. Khan (2008)Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells
Yan-liang Zhang, Yong Dai, Yuanshuai Huang, Liguo Ma, Yibing Yin, M. Tang, Chengxiao Hu (2009)Microarray profile of micro‐ribonucleic acid in tumor tissue from cervical squamous cell carcinoma without human papillomavirus
Journal of Obstetrics and Gynaecology Research, 35
S. Griffiths-Jones, R. Grocock, S. Dongen, A. Bateman, Anton Enright (2005)miRBase: microRNA sequences, targets and gene nomenclature
Nucleic Acids Research, 34
(2007)Robbins basic pathology. PA: Saunders/Elsevier. xiv, Philadelphia
A. Hui, M. Lenarduzzi, Tiffaney Krushel, L. Waldron, M. Pintilie, W. Shi, B. Perez–Ordoñez, I. Jurisica, B. O'Sullivan, J. Waldron, P. Gullane, B. Cummings, Fei-Fei Liu (2010)Comprehensive MicroRNA Profiling for Head and Neck Squamous Cell Carcinomas
Clinical Cancer Research, 16
K. Münger, Werness Ba, N. Dyson, W. Phelps, E. Harlow, P. Howley (1989)Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.
The EMBO Journal, 8
A. Tong, P. Fulgham, C. Jay, Patrick Chen, I. Khalil, Shengnan Liu, N. Senzer, A. Eklund, J. Han, J. Nemunaitis (2009)MicroRNA profile analysis of human prostate cancers
Cancer Gene Therapy, 16
S. Yoshida, N. Kajitani, A. Satsuka, Hiroyasu Nakamura, H. Sakai (2008)Ras Modifies Proliferation and Invasiveness of Cells Expressing Human Papillomavirus Oncoproteins
Journal of Virology, 82
R. Winn, M. Scoyk, M. Hammond, K. Rodriguez, J. Crossno, L. Heasley, R. Nemenoff (2006)Antitumorigenic Effect of Wnt 7a and Fzd 9 in Non-small Cell Lung Cancer Cells Is Mediated through ERK-5-dependent Activation of Peroxisome Proliferator-activated Receptor γ*
Journal of Biological Chemistry, 281
Jeong-Won Lee, Young-Ae Park, Jung-Joo Choi, Y. Lee, C. Kim, C. Choi, Tae-Joong Kim, N. Lee, Byoung-Gie Kim, D. Bae (2011)The expression of the miRNA-200 family in endometrial endometrioid carcinoma.
Gynecologic oncology, 120 1
P. Descargues, C. Deraison, C. Bonnart, Maaike Kreft, M. Kishibe, A. Ishida‐Yamamoto, P. Elias, Y. Barrandon, G. Zambruno, A. Sonnenberg, A. Hovnanian (2005)Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity
Nature Genetics, 37
P. Linsley, Janell Schelter, J. Burchard, M. Kibukawa, Melissa Martin, S. Bartz, Jason Johnson, Jordan Cummins, C. Raymond, H. Dai, Nelson Chau, M. Cleary, A. Jackson, M. Carleton, Lee Lim (2007)Transcripts Targeted by the MicroRNA-16 Family Cooperatively Regulate Cell Cycle Progression
Molecular and Cellular Biology, 27
Anny Shai, T. Brake, C. Somoza, P. Lambert (2007)The human papillomavirus E6 oncogene dysregulates the cell cycle and contributes to cervical carcinogenesis through two independent activities.
Cancer research, 67 4
D. Gius, Margo Funk, E. Chuang, E. Chuang, Sheng-Chun Feng, P. Huettner, L. Nguyen, C. Bradbury, Mark Mishra, Shuping Gao, B. Buttin, D. Cohn, M. Powell, N. Horowitz, B. Whitcomb, J. Rader (2007)Profiling microdissected epithelium and stroma to model genomic signatures for cervical carcinogenesis accommodating for covariates.
Cancer research, 67 15
Morgan Davidson, J. Larsen, I. Yang, N. Hayward, B. Clarke, E. Duhig, Linda Passmore, R. Bowman, K. Fong (2010)MicroRNA-218 Is Deleted and Downregulated in Lung Squamous Cell Carcinoma
PLoS ONE, 5
S. Volinia, G. Calin, Chang-gong Liu, S. Ambs, A. Cimmino, F. Petrocca, R. Visone, M. Iorio, C. Roldo, M. Ferracin, R. Prueitt, N. Yanaihara, G. Lanza, A. Scarpa, A. Vecchione, M. Negrini, C. Harris, C. Croce (2006)A microRNA expression signature of human solid tumors defines cancer gene targets
Proceedings of the National Academy of Sciences of the United States of America, 103
Steven Johnson, H. Grosshans, Jaclyn Shingara, M. Byrom, R. Jarvis, Angie Cheng, E. Labourier, K. Reinert, D. Brown, F. Slack (2005)RAS Is Regulated by the let-7 MicroRNA Family
Libing Song, Quan Huang, Kun Chen, Liping Liu, Chuyong Lin, Ting Dai, Chunping Yu, Zhiqiang Wu, Jun Li (2010)miR-218 inhibits the invasive ability of glioma cells by direct downregulation of IKK-β.
Biochemical and biophysical research communications, 402 1
A. Sarver, A. French, Pedro Borralho, V. Thayanithy, A. Oberg, K. Silverstein, B. Morlan, S. Riska, L. Boardman, J. Cunningham, Subbaya Subramanian, Liang Wang, T. Smyrk, C. Rodrigues, S. Thibodeau, C. Steer (2009)Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
BMC Cancer, 9
(2010)doi:10.1186/1750-9378-5-S1-A55 Cite this article as: Gardiner et al.: MicroRNA analysis in human papillomavirus (HPV)-associated cervical neoplasia and cancer
Q. Rao, Hui Zhou, Yong-pai Peng, Jing Li, Zhong-qiu Lin (2012)Aberrant microRNA expression in human cervical carcinomas
Medical Oncology, 29
M. Scheffner, B. Werness, J. Huibregtse, A. Levine, P. Howley (1990)The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
Ji-guang Zhang, Jian-Jun Wang, Feng Zhao, Quan Liu, Ke Jiang, Guanghai Yang (2010)MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC).
Clinica chimica acta; international journal of clinical chemistry, 411 11-12
T. Ueda, S. Volinia, H. Okumura, M. Shimizu, C. Taccioli, S. Rossi, H. Alder, Chang-gong Liu, N. Oue, W. Yasui, Kazuhiro Yoshida, H. Sasaki, S. Nomura, Y. Seto, M. Kaminishi, G. Calin, C. Croce (2010)Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis.
The Lancet. Oncology, 11 2
Gardiner et al. Infectious Agents and Cancer 2010, 5(Suppl 1):A55 http://www.infectagentscancer.com/content/5/S1/A55 MEETING ABSTRACTS Open Access MicroRNA analysis in human papillomavirus (HPV)-associated cervical neoplasia and cancer 1* 2 2 2 2 3 Amy S Gardiner , William C McBee Jr. , Robert P Edwards , Marshall Austin , Jamie L Lesnock , Rohit Bhargava , 2 1 Richard Guido , Saleem A Khan th From 12 International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI) Bethesda, MD, USA. 26-27 April, 2010 Author details MicroRNAs (miRNAs) are ~22 nt single-stranded, non- Department of Microbiology and Molecular Genetics, University of protein-coding RNAs that generally negatively regulate Pittsburgh School of Medicine, Pittsburgh, PA, USA. Division of Gynecologic their target mRNAs at a posttranscriptional level. Differ- Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Women’s Hospital of the University of Pittsburgh Medical ential expression of miRNAs has been observed in many Center, Pittsburgh, PA, USA. Department of Pathology, Magee-Women’s human cancers. To study their potential role in the Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA, USA. pathogenesis of human papillomavirus (HPV) type 16- Published: 11 October 2010 associated cervical neoplasia and cancer, we analyzed miRNA expression in cervical tissue from the normal cervix, moderate/severe dysplasia, and invasive squa- doi:10.1186/1750-9378-5-S1-A55 mous cell carcinoma. Using RNA from 6 cervical can- Cite this article as: Gardiner et al.: MicroRNA analysis in human cers, 3 dysplasias, and 4 normal samples and the papillomavirus (HPV)-associated cervical neoplasia and cancer. Infectious TaqMan® MicroRNA Arrays, we found that 18 miRNAs Agents and Cancer 2010 5(Suppl 1):A55. were overexpressed and 2 underexpressed in cervical cancer compared to the normal cervical tissue (p<0.05). We further found that 9 miRNAs (miRs-16, 21, 106b, 124, 135b, 223, 301b, 449a, and 141) were consistently overexpressed and 2 miRNAs (miRs-218 and 433) were consistently underexpressed in cervical cancer compared to the normal tissue. MiRNA expression in dysplasia samples was most similar to the normal tissue, with the exception of the overexpression of miR-16, miR-141, and miR-449a, and the underexpression of miR-218 and miR-433. Our results suggest that five miRNAs may have potential as markers for progression of dysplasia to invasive cervical disease. Submit your next manuscript to BioMed Central and take full advantage of: Acknowledgements This article has been published as part of Infectious Agents and Cancer • Convenient online submission th Volume 5 Supplement 1, 2010: Proceedings of the 12 International • Thorough peer review Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI). The full contents of the supplement are • No space constraints or color ﬁgure charges available online at http://www.biomedcentral.com/1750-9378/5?issue=S1. • Immediate publication on acceptance • Inclusion in PubMed, CAS, Scopus and Google Scholar *Correspondence: email@example.com 1 • Research which is freely available for redistribution Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA Full list of author information is available at the end of the article Submit your manuscript at www.biomedcentral.com/submit © 2010 Gardiner et al; licensee BioMed Central Ltd.
Infectious Agents and Cancer – Springer Journals
Published: Oct 11, 2010
Access the full text.
Sign up today, get DeepDyve free for 14 days.