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Nonclinical Statistics for Pharmaceutical and Biotechnology IndustriesStatistical Methods for Drug Discovery

Nonclinical Statistics for Pharmaceutical and Biotechnology Industries: Statistical Methods for... [This chapter is a broad overview of the drug discovery process and areas where statistical input can have a key impact. The focus is primarily in a few key areas: target discovery, compound screening/optimization, and the characterization of important properties. Special attention is paid to working with assay data and phenotypic screens. A discussion of important skills for a nonclinical statistician supporting drug discovery concludes the chapter.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

Nonclinical Statistics for Pharmaceutical and Biotechnology IndustriesStatistical Methods for Drug Discovery

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Publisher
Springer International Publishing
Copyright
© Springer International Publishing Switzerland 2016
ISBN
978-3-319-23557-8
Pages
53 –81
DOI
10.1007/978-3-319-23558-5_4
Publisher site
See Chapter on Publisher Site

Abstract

[This chapter is a broad overview of the drug discovery process and areas where statistical input can have a key impact. The focus is primarily in a few key areas: target discovery, compound screening/optimization, and the characterization of important properties. Special attention is paid to working with assay data and phenotypic screens. A discussion of important skills for a nonclinical statistician supporting drug discovery concludes the chapter.]

Published: Dec 29, 2015

Keywords: Assay Development; Assay Validation; GWAS; Bioassay; Target; ADME; Dose Response

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