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Pergolide to Augment the Effectiveness of Antidepressants: Clinical Experience and a Small Double-Blind Study

Pergolide to Augment the Effectiveness of Antidepressants: Clinical Experience and a Small... To attempt to confirm a prior report that pergolide can augment the efficacy of antidepressants in refractory patients, pergolide was administered to 12 patients receiving antidepressants. Eight patients were involved in a placebo-controlled evaluation of pergolide; the others were prescribed pergolide clinically. Results showed no evidence of benefit, so the double-blind study has been discontinued. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Clinical Psychiatry Springer Journals

Pergolide to Augment the Effectiveness of Antidepressants: Clinical Experience and a Small Double-Blind Study

Mattes, Jeffrey
Annals of Clinical Psychiatry , Volume 9 (2) – Sep 18, 2004
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Publisher
Springer Journals
Copyright
Copyright © 1997 by American Academy of Clinical Psychiatrists
Subject
Medicine & Public Health; Neurology; Psychiatry; Psychopharmacology
ISSN
1040-1237
eISSN
1573-3238
DOI
10.1023/A:1026253202366
Publisher site
See Article on Publisher Site

Abstract

To attempt to confirm a prior report that pergolide can augment the efficacy of antidepressants in refractory patients, pergolide was administered to 12 patients receiving antidepressants. Eight patients were involved in a placebo-controlled evaluation of pergolide; the others were prescribed pergolide clinically. Results showed no evidence of benefit, so the double-blind study has been discontinued.

Journal

Annals of Clinical Psychiatry – Springer Journals

Published: Sep 18, 2004

References

  • Pergolide: An antidepressant adjuvant for mood disorders?
    Bouckoms, A; Mangini, L