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Persistent Endocrine-Disrupting Chemicals and Fatty Liver Disease

Persistent Endocrine-Disrupting Chemicals and Fatty Liver Disease Curr Envir Health Rpt (2017) 4:439–449 DOI 10.1007/s40572-017-0166-8 SYNTHETIC CHEMICALS AND HEALTH (J HERBSTMAN AND T JAMES-TODD, SECTION EDITORS) Persistent Endocrine-Disrupting Chemicals and Fatty Liver Disease 1 1 1 Andrea L. Deierlein & Sarah Rock & Sally Park Published online: 4 October 2017 Springer International Publishing AG 2017 Abstract sample of gastric bypass surgery patients, examined sex- Purpose of Review Non-alcoholic fatty liver disease specific associations of POPs and liver enzymes, finding ad- (NAFLD) is the most prominent chronic liver disease in verse associations among women only. The noticeable lack of Western countries, affecting approximately 25% of the popu- studies investigating how differences (i.e., biochemical, phys- lation worldwide. Sex-specific differences in the development iological, and behavioral) between men and women may in- of NAFLD are apparent. While obesity and insulin resistance fluence associations of pEDCs and NAFLD represents a large are major contributors to the increasing prevalence of research gap in environmental health. Sexual dimorphism in NAFLD, a growing body of literature suggests that exposure metabolic processes throughout the body, including the liver, to persistent endocrine-disrupting chemicals (pEDCs) may al- is established but often overlooked in the designs and analyses so play a role. This review summarizes recent (2011 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Environmental Health Reports Springer Journals

Persistent Endocrine-Disrupting Chemicals and Fatty Liver Disease

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References (95)

Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer International Publishing AG
Subject
Biomedicine; Pharmacology/Toxicology; Medicine/Public Health, general; Environmental Health
eISSN
2196-5412
DOI
10.1007/s40572-017-0166-8
pmid
28980219
Publisher site
See Article on Publisher Site

Abstract

Curr Envir Health Rpt (2017) 4:439–449 DOI 10.1007/s40572-017-0166-8 SYNTHETIC CHEMICALS AND HEALTH (J HERBSTMAN AND T JAMES-TODD, SECTION EDITORS) Persistent Endocrine-Disrupting Chemicals and Fatty Liver Disease 1 1 1 Andrea L. Deierlein & Sarah Rock & Sally Park Published online: 4 October 2017 Springer International Publishing AG 2017 Abstract sample of gastric bypass surgery patients, examined sex- Purpose of Review Non-alcoholic fatty liver disease specific associations of POPs and liver enzymes, finding ad- (NAFLD) is the most prominent chronic liver disease in verse associations among women only. The noticeable lack of Western countries, affecting approximately 25% of the popu- studies investigating how differences (i.e., biochemical, phys- lation worldwide. Sex-specific differences in the development iological, and behavioral) between men and women may in- of NAFLD are apparent. While obesity and insulin resistance fluence associations of pEDCs and NAFLD represents a large are major contributors to the increasing prevalence of research gap in environmental health. Sexual dimorphism in NAFLD, a growing body of literature suggests that exposure metabolic processes throughout the body, including the liver, to persistent endocrine-disrupting chemicals (pEDCs) may al- is established but often overlooked in the designs and analyses so play a role. This review summarizes recent (2011

Journal

Current Environmental Health Reports – Springer Journals

Published: Oct 4, 2017

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